中国肿瘤临床
中國腫瘤臨床
중국종류림상
CHINESE JOURNAL OF CLINICAL ONCOLOGY
2015年
17期
845-849
,共5页
结直肠癌肝转移%外科手术%治疗
結直腸癌肝轉移%外科手術%治療
결직장암간전이%외과수술%치료
colorectal cancer liver metastasis%surgical resection%therapy
目前手术切除是结直肠癌肝转移（CRLM）唯一具有治愈可能的治疗方式。近年来随着全身化疗及靶向药物的发展、肝动脉灌注化疗的应用，对于CRLM治疗的有效率明显升高，通过手术获益的患者逐渐增多；而如射频消融、二步切除等外科技术的进步，也为更多CRLM患者提供了治愈的机会。多学科诊疗模式（MDT）也为更多CRLM患者的个体化诊治创造了机会，使未来CRLM的治疗向更加精准的方向发展。
目前手術切除是結直腸癌肝轉移（CRLM）唯一具有治愈可能的治療方式。近年來隨著全身化療及靶嚮藥物的髮展、肝動脈灌註化療的應用，對于CRLM治療的有效率明顯升高，通過手術穫益的患者逐漸增多；而如射頻消融、二步切除等外科技術的進步，也為更多CRLM患者提供瞭治愈的機會。多學科診療模式（MDT）也為更多CRLM患者的箇體化診治創造瞭機會，使未來CRLM的治療嚮更加精準的方嚮髮展。
목전수술절제시결직장암간전이（CRLM）유일구유치유가능적치료방식。근년래수착전신화료급파향약물적발전、간동맥관주화료적응용，대우CRLM치료적유효솔명현승고，통과수술획익적환자축점증다；이여사빈소융、이보절제등외과기술적진보，야위경다CRLM환자제공료치유적궤회。다학과진료모식（MDT）야위경다CRLM환자적개체화진치창조료궤회，사미래CRLM적치료향경가정준적방향발전。
Surgical resection is currently the only cure treatment for colorectal carcinoma liver metastasis (CRLM). The efficien-cy of surgical resection has improved with the development of systemic chemotherapy and targeted drugs and the application of hepatic arterial infusion chemotherapy in recent years. The number of patients benefiting from surgery has gradually increased. The progression of surgical techniques such as radiofrequency ablation and staged hepatectomy provides chances of cure for patients with CRLM. Multi-disciplinary team creates the opportunity of individual diagnosis and treatment for growing number of patients with CRLM, which, in turn, promotes the treatment of CRLM to a more precise future.
