CAJ | 학술논문

目的：探讨应用序贯透析治疗顽固性腹水的临床效果。方法将20例顽固性腹水患者作为研究对象，经常规治疗无效后应用序贯透析治疗并在透析过程中输注人血白蛋白10g或同型血浆200mL；2～3次/周，直到腹水基本消退。观察患者治疗前后体质量、腹围、24h尿量、肝功能、肾功能、血电解质等的变化以及不良反应。结果共治疗20例（72人次），患者腹水消退率达100%，B型超声检查患者腹水均明显消退，均无不良反应；与治疗前比较，患者治疗后体质量下降、腹围缩小、白蛋白升高、尿量增加、肝功能好转，差异均有统计学意义（P＜0.05）。结论应用序贯透析对顽固性腹水操作简单，安全有效，值得临床推广应用。
목적：탐토응용서관투석치료완고성복수적림상효과。방법장20례완고성복수환자작위연구대상，경상규치료무효후응용서관투석치료병재투석과정중수주인혈백단백10g혹동형혈장200mL；2～3차/주，직도복수기본소퇴。관찰환자치료전후체질량、복위、24h뇨량、간공능、신공능、혈전해질등적변화이급불량반응。결과공치료20례（72인차），환자복수소퇴솔체100%，B형초성검사환자복수균명현소퇴，균무불량반응；여치료전비교，환자치료후체질량하강、복위축소、백단백승고、뇨량증가、간공능호전，차이균유통계학의의（P＜0.05）。결론응용서관투석대완고성복수조작간단，안전유효，치득림상추엄응용。
Objective To investigate the clinical effect of applying sequential dialysis in the treatment of refractory ascites.Methods20 cases of patients with refractory ascites as the research object, regular treatment is invalid after the application of sequential dialysis treatment and during dialysis infusion Human Albumin 10g or plasma 200mL; 2 to 3 times a week, until the ascites disappeared. To observe the changes of body weight, abdominal circumference of patients before and after treatment, 24 h urinary volume, liver function, renal function, blood electrolytes and adverse reaction.Results 20 cases were treated(72 times), patients with ascites extinction rate to 100%, type B in ascites of patients with ultrasound were significantly subsided, there were no adverse reaction; compared with that before treatment, the treatment of patients with body weight, abdominal circumference reduced albumin increased, decreased, urine volume increased, the improvement of liver function, the difference was statistically significant(P<0.05). Conclusion The application of sequential dialysis on refractory ascites is simple in operation, safe and effective, worthy of clinical application.