CAJ | 학술논문

目的：观察高压氧（HBO）联合药物治疗幽门螺旋杆菌（Hp）阳性患者的临床疗效。方法将116例Hp阳性患者随机分为高压氧联合药物组（n=58，治疗组）和单纯药物组（n=58，对照组），2个疗程后胃镜复查，比较两组患者治疗前后溃疡大小及Hp的检出率。结果与对照组比较，治疗组患者溃疡的大小及Hp检出率明显减小（P＜0.05），有效率升高（94% vs 69%，P＜0.05），复发率降低（13.20% vs 34.69%，P＜0.05），差异有统计学意义（P＜0.05）。结论高压氧联合药物治疗Hp阳性患者的疗效确切，复发率低，值得在临床推广应用。
목적：관찰고압양（HBO）연합약물치료유문라선간균（Hp）양성환자적림상료효。방법장116례Hp양성환자수궤분위고압양연합약물조（n=58，치료조）화단순약물조（n=58，대조조），2개료정후위경복사，비교량조환자치료전후궤양대소급Hp적검출솔。결과여대조조비교，치료조환자궤양적대소급Hp검출솔명현감소（P＜0.05），유효솔승고（94% vs 69%，P＜0.05），복발솔강저（13.20% vs 34.69%，P＜0.05），차이유통계학의의（P＜0.05）。결론고압양연합약물치료Hp양성환자적료효학절，복발솔저，치득재림상추엄응용。
Objective To observe clinical effect of the hyperbaric oxygen (HBO)combined drug treatment of helicobacter pylori (Hp)-positive patients.Methods116 cases of Hp positive patients were randomly into hyperbaric oxygen combined drug group (n=58, the treatment group) and simple drug group (n=58, the control group). After two courses oftreatment,we compared ulcer size and Hp detection rate of two groups of patients through thegastroscope before and after treatment. Results Compared with control group, ulcer sizes and Hp detection rate were significantly reduced (P<0.05),and there were higher effective rate(94% vs 69%,P<0.05) and lower relapse rate (13.20% vs 34.69%,P<0.05) in the treatment group. The difference was statistically significant(P<0.05).Conclusion The treatment of the hyperbaric oxygen (HBO) combined drug treatment of helicobacter pylori (Hp)-positive patients is effective, and its recurrence rate is low. Therefore, the method is worthy of clinical application.