CAJ | 학술논문

目的：探讨糖尿病患者白内障术后干眼症状、焦虑水平、炎症因子三者之间的关系。方法糖尿病患者晶状体超声乳化术后96例(96眼)，通过汉密尔顿焦虑量表分为焦虑组及非焦虑组。于术后1周行泪膜破裂时间测定( BUT)、基础泪液分泌试验( SIt)、角膜荧光素染色( FL)、炎性因子检测及焦虑水平、干眼主观症状评分。结果糖尿病患者超声乳化术后1周，焦虑组与非焦虑组术后干眼主观症状、泪液指标( BUT、SIt、FL)及血清炎症因子中白细胞介素-1β( IL-1β)、白细胞介素-6(IL-6)及肿瘤坏死因子(TNF)含量的比较，差异均有统计学意义(P<0.05)；患者干眼主观症状与焦虑水平、炎症因子指标均呈正相关(P<0.05)。结论焦虑状态可激发炎症因子加剧糖尿病患者白内障术后的干眼症状。
목적：탐토당뇨병환자백내장술후간안증상、초필수평、염증인자삼자지간적관계。방법당뇨병환자정상체초성유화술후96례(96안)，통과한밀이돈초필량표분위초필조급비초필조。우술후1주행루막파렬시간측정( BUT)、기출루액분비시험( SIt)、각막형광소염색( FL)、염성인자검측급초필수평、간안주관증상평분。결과당뇨병환자초성유화술후1주，초필조여비초필조술후간안주관증상、루액지표( BUT、SIt、FL)급혈청염증인자중백세포개소-1β( IL-1β)、백세포개소-6(IL-6)급종류배사인자(TNF)함량적비교，차이균유통계학의의(P<0.05)；환자간안주관증상여초필수평、염증인자지표균정정상관(P<0.05)。결론초필상태가격발염증인자가극당뇨병환자백내장술후적간안증상。
Objective To investigate the correlation of dry eye symptom, anxiety level and inflammatory factor in diabetic patients after phacoemulsification for cataract. Methods Ninty-six eyes of 96 diabetic patients after phacoemulsification were divided into anxiety groups and non-anxiety groups according to Hamilton Anxiety Scale. Tear film breakup time ( BUT) , Schirmer test( SIt) , Cornea fluorescein staining ( FL) , inflammatory factor detection, anxiety level and dry eye subjective symptom scores were evaluated one week after operation. Results Dry eye subjective symptom, tear film indexes ( BUT, Sit and FL) and inflammatory factor ( IL-1β, IL-6, tumor necrosis factor) in postoperative one week showed statistically significant differences between anxiety and non-anxiety group (P<0. 05). The dry eye subjective symptom was positively correlated to anxiety level as well as inflammatory factor (P<0. 05). Conclusion Anxiety could aggravate dry eye subjective symptom in diabetic patients after phacoemulsification by stimulating the inflammatory factor.