CAJ | 학술논문

目的：探讨非肌层浸润膀胱尿路上皮癌二次电切术的临床价值。方法将60例非肌层浸润膀胱尿路上皮癌患者随机分为观察组和对照组2组，每组30例，均给予尿道电切术，观察组行二次电切术。比较2组复发情况，并对比首次电切与二次电切的病理结果。结果观察组复发4例（13．3％），出现复发时间（6．3±1．2）个月，其中原电切部位复发1例（3．3％），其他部位复发3例（10．0％），单发1例，多发2例。对照组复发13例（43．3％），出现复发时间（2．4±0．9）个月，其中原电切部位复发7例（23．3％），其他部位复发6例（20．0％），单发4例，多发2例。以上差异具有统计学意义（ P＜0．05）。观察组初次电切的病理结果显示，Ta期4例（13．3％），T1期26例（86．7％）。二次电切病理结果为Ta期2例（6．7％），T1期19例（63．3％），T2期9例（30．0％）。1例Ta期升为T1期，1例Ta期升为T2期，8例T1期升为T2期。以上差异均有统计学意义（ P＜0．05）。结论二次电切术能够有效降低非肌层浸润膀胱尿路上皮癌的复发率，同时对纠正病理结果具有重要临床价值。
목적：탐토비기층침윤방광뇨로상피암이차전절술적림상개치。방법장60례비기층침윤방광뇨로상피암환자수궤분위관찰조화대조조2조，매조30례，균급여뇨도전절술，관찰조행이차전절술。비교2조복발정황，병대비수차전절여이차전절적병리결과。결과관찰조복발4례（13．3％），출현복발시간（6．3±1．2）개월，기중원전절부위복발1례（3．3％），기타부위복발3례（10．0％），단발1례，다발2례。대조조복발13례（43．3％），출현복발시간（2．4±0．9）개월，기중원전절부위복발7례（23．3％），기타부위복발6례（20．0％），단발4례，다발2례。이상차이구유통계학의의（ P＜0．05）。관찰조초차전절적병리결과현시，Ta기4례（13．3％），T1기26례（86．7％）。이차전절병리결과위Ta기2례（6．7％），T1기19례（63．3％），T2기9례（30．0％）。1례Ta기승위T1기，1례Ta기승위T2기，8례T1기승위T2기。이상차이균유통계학의의（ P＜0．05）。결론이차전절술능구유효강저비기층침윤방광뇨로상피암적복발솔，동시대규정병리결과구유중요림상개치。
Objective To explore the clinical value of Re-transurethral resection of bladder tumor( TURBT) for patients with non -muscle invasive urothelial carcinoma of urinary bladder.Methods From February 2004 to January 2013 our hospital treated 60 cases of non muscle invasive bladder cancer patients which were randomly divided into two groups, compared two groups of patients with recurrence, and compare the pathological results first and transurethral electric resection two times.Results 4 cases of the experimental group of recurrence (13.3%), the average time to relapse(6.3 ±1.2) month, of which the original electric cutting site recurrence in 1 case(3.3%), 3 cases of recurrence in other parts of the body ( 10%) , 1 case with single and multiple in 2 cases; the control group of 13 cases of recurrence (43.3%), the average time of recurrence(2.4 ±0.9) month, of which the original electric cutting site recurrence in 7 cases(23.3%), 6 cases of recurrence in other parts of the body(20%), 4 case of single and multiple in 2 cases.Statistically there is significant differences (P<0.05).Experimental pathology group first electric cutting results, 4 cases of Ta stage(13.3%), T1 in 26 cases(86.7%).The two e-lectricity cut pathological results for Ta period of 2 cases(6.7%), 19 cases of T1 stage(63.3%), 9 cases of T2 stage(30%).1 patient with stage Ta or stage T1 , 1 patient with stage Ta or stage T2;8 patients with stage T1 or stage T2 .These differences were statistically significant ( P<0.05) .Conclusion Re-TURBT can effectively reduce the non muscle invasive urothelial carcinoma of the urinary bladder recurrence rate, at the same time, it has an important clinical value to correct the pathologic results.