中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2015年
15期
118-120
,共3页
扩张型心肌病%心力衰竭%丙种球蛋白
擴張型心肌病%心力衰竭%丙種毬蛋白
확장형심기병%심력쇠갈%병충구단백
Dilated cardiomyopathy%Heart failure%Gamma globulin
目的：探讨丙种球蛋白疗法对扩张型心肌病的疗效。方法选择2012年1月～2014年9月于我院住院治疗的49例扩张型心肌病合并心力衰竭患者为研究对象。对照组患者23例，使用传统抗心衰治疗；观察组患者26例，在此基础上合并使用丙种球蛋白治疗。并对两组患者临床资料进行分析，1个月后对其进行心功能评价。结果本组研究患者均表现为心力衰竭症状及体征，临床症状表现为水肿35例（71.43%），气促27例（55.10%），纳差18例（36.73%）等。心尖部杂音为最常见体征39例（79.59%）。治疗1个月后，两组患者上述症状均较治疗前减轻。治疗后观察组的6min最大步行距离、左心室舒张末期内径（LVEDD）及左心室射血分数（LVEF）等心功能指标均较对照组明显改善，差异有统计学意义（P＜0.05）。结论丙种球蛋白疗法可显著改善扩张型心肌病患者心功能，值得临床推广。
目的：探討丙種毬蛋白療法對擴張型心肌病的療效。方法選擇2012年1月～2014年9月于我院住院治療的49例擴張型心肌病閤併心力衰竭患者為研究對象。對照組患者23例，使用傳統抗心衰治療；觀察組患者26例，在此基礎上閤併使用丙種毬蛋白治療。併對兩組患者臨床資料進行分析，1箇月後對其進行心功能評價。結果本組研究患者均錶現為心力衰竭癥狀及體徵，臨床癥狀錶現為水腫35例（71.43%），氣促27例（55.10%），納差18例（36.73%）等。心尖部雜音為最常見體徵39例（79.59%）。治療1箇月後，兩組患者上述癥狀均較治療前減輕。治療後觀察組的6min最大步行距離、左心室舒張末期內徑（LVEDD）及左心室射血分數（LVEF）等心功能指標均較對照組明顯改善，差異有統計學意義（P＜0.05）。結論丙種毬蛋白療法可顯著改善擴張型心肌病患者心功能，值得臨床推廣。
목적：탐토병충구단백요법대확장형심기병적료효。방법선택2012년1월～2014년9월우아원주원치료적49례확장형심기병합병심력쇠갈환자위연구대상。대조조환자23례，사용전통항심쇠치료；관찰조환자26례，재차기출상합병사용병충구단백치료。병대량조환자림상자료진행분석，1개월후대기진행심공능평개。결과본조연구환자균표현위심력쇠갈증상급체정，림상증상표현위수종35례（71.43%），기촉27례（55.10%），납차18례（36.73%）등。심첨부잡음위최상견체정39례（79.59%）。치료1개월후，량조환자상술증상균교치료전감경。치료후관찰조적6min최대보행거리、좌심실서장말기내경（LVEDD）급좌심실사혈분수（LVEF）등심공능지표균교대조조명현개선，차이유통계학의의（P＜0.05）。결론병충구단백요법가현저개선확장형심기병환자심공능，치득림상추엄。
ObjectiveTo explore the clinical effect of gamma globulin in the treatment of dilated cardiomyopathy. Methods49 patients with dilated cardiomyopathy who were hospitalized and treated in our hospital from January 2012 to September 2014 were selected as research subjects.23 patients of control group were treated with conventional anti-heart failure therapy,and 26 patients of observation group were further treated with gamma globulin.Clinical data of two groups were analyzed, and cardiac function was evaluated after one month. ResultsAll patients in this group had symptoms of heart failure,and the clinical symptoms included 35 patients with edema (71.43%),27 patients with shortness of breath (55.10%),18 patients with poor appetite (36.73%) and so on.The most common sign was apical murmur (79.59%).Symptoms of patients of two groups were both alleviated after one month treatment.The longest walking distance in 6 minutes,left ventricular end diastolic dimension (LVEDD),left ventricular ejection fraction (LVEF) and other cardiac function index of observation group after treatment were significantly improved compared with those of control group,and the difference was statistically significant (P<0.05).Conclusion Gamma globulin therapy can significantly improve cardiac function of patients with dilated cardiomyopathy,which is worthy of clinical application.
