中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2015年
15期
98-100
,共3页
男性念珠菌尿道炎%氟康唑%伊曲康唑%临床疗效
男性唸珠菌尿道炎%氟康唑%伊麯康唑%臨床療效
남성념주균뇨도염%불강서%이곡강서%림상료효
Male candidal urethritis%Fluconazole%Itraconazole%Clinical effect
目的：探讨应用氟康唑与伊曲康唑治疗男性念珠菌尿道炎的临床疗效。方法本研究选取2013年6月~2014年10月来我院性病门诊就诊的男性患者75例，随机分为观察组38例及对照组37例。对照组采用氟康唑治疗，观察组在对照组基础上给予伊曲康唑治疗。对两组患者近期疗效，远期疗效及不良反应发生率等相关指标进行观察。结果观察组患者的患者临床近期疗效为89.47%，对照组为86.49%，两组比较，差异无统计学意义（P＞0.05）。观察组远期疗效为94.74%，明显高于对照组的81.08%，两组比较，差异有统计学意义（P＜0.05）。观察组不良反应发生率为7.89%，对照组不良反应发生率为18.92%，两组比较差异有统计学意义（P＜0.05）。结论应用氟康唑与伊曲康唑联合治疗男性念珠菌尿道炎可以提高患者远期疗效，减少不良反应发生率，值得临床推广应用。
目的：探討應用氟康唑與伊麯康唑治療男性唸珠菌尿道炎的臨床療效。方法本研究選取2013年6月~2014年10月來我院性病門診就診的男性患者75例，隨機分為觀察組38例及對照組37例。對照組採用氟康唑治療，觀察組在對照組基礎上給予伊麯康唑治療。對兩組患者近期療效，遠期療效及不良反應髮生率等相關指標進行觀察。結果觀察組患者的患者臨床近期療效為89.47%，對照組為86.49%，兩組比較，差異無統計學意義（P＞0.05）。觀察組遠期療效為94.74%，明顯高于對照組的81.08%，兩組比較，差異有統計學意義（P＜0.05）。觀察組不良反應髮生率為7.89%，對照組不良反應髮生率為18.92%，兩組比較差異有統計學意義（P＜0.05）。結論應用氟康唑與伊麯康唑聯閤治療男性唸珠菌尿道炎可以提高患者遠期療效，減少不良反應髮生率，值得臨床推廣應用。
목적：탐토응용불강서여이곡강서치료남성념주균뇨도염적림상료효。방법본연구선취2013년6월~2014년10월래아원성병문진취진적남성환자75례，수궤분위관찰조38례급대조조37례。대조조채용불강서치료，관찰조재대조조기출상급여이곡강서치료。대량조환자근기료효，원기료효급불량반응발생솔등상관지표진행관찰。결과관찰조환자적환자림상근기료효위89.47%，대조조위86.49%，량조비교，차이무통계학의의（P＞0.05）。관찰조원기료효위94.74%，명현고우대조조적81.08%，량조비교，차이유통계학의의（P＜0.05）。관찰조불량반응발생솔위7.89%，대조조불량반응발생솔위18.92%，량조비교차이유통계학의의（P＜0.05）。결론응용불강서여이곡강서연합치료남성념주균뇨도염가이제고환자원기료효，감소불량반응발생솔，치득림상추엄응용。
Objective To explore the clinical effect of fluconazole and itraconazole in the treatment of male candidal urethritis.Methods 75 male patients were selected in this study from 2013 June to 2014 October in STD clinic of our hospital, and randomly divided into the observation group of 38 cases and control group of 37 cases. The control group was treated with fluconazole, the observation group was treated with itraconazole on the basis of the control group. The short-term and long-term efficacy and toxicitiesassociated index of two groups of patients were observed.ResultsThe short-term curative effect of patients in the observation group was 89.47%, the control group was 86.49%, the difference was not statistically significant between the two groups(P>0.05).The long-term efficacy of observation group was 94.74%, significantly higher than the control group of 81.08%, the difference was statistically significant between the two groups(P<0.05). The incidence of adverse reaction in the observation group was 7.89%, the control group was 18.92%, there was significant difference between the two groups(P<0.05).Conclusion Fluconazole and itraconazole in the treatment of male candidal urethritis can improve long-term efficacy, reduce the incidence of adverse reactions, it is worthy of clinical application.
