CAJ | 학술논문

目的：观察注射用复方甘草酸苷联合阿昔洛韦治疗带状疱疹及后遗神经痛的临床疗效。方法选取2013年1月～2014年1月我院住院治疗的带状疱疹患者60例作为研究对象，随机分为观察组（n=30，采用注射用复方甘草酸苷联合阿昔洛韦治疗）和对照组（n=30，采用阿昔洛韦治疗），比较两组治疗后的总有效率、两组的止疱时间、结痂时间、止痛时间。结果观察组治疗后的总有效率达90%，显著高于对照组治疗后的总有效率（73.3%），组间比较，差异具有统计学意义（x2=6.387，P＜0.05）。观察组的止疱时间、结痂时间、止痛时间均分别为（2.56±1.07）d、（3.23±0.85）d、（5.61±1.07）d，对照组的止疱时间、结痂时间、止痛时间均分别为（4.32±1.12）d、（5.96±1.03）d、（8.93±1.02）d、两组比较具有统计学差异（P＜0.05）。结论注射用复方甘草酸苷联合阿昔洛韦治疗带状疱疹及后遗神经痛具有较好的疗效，值得推广。
목적：관찰주사용복방감초산감연합아석락위치료대상포진급후유신경통적림상료효。방법선취2013년1월～2014년1월아원주원치료적대상포진환자60례작위연구대상，수궤분위관찰조（n=30，채용주사용복방감초산감연합아석락위치료）화대조조（n=30，채용아석락위치료），비교량조치료후적총유효솔、량조적지포시간、결가시간、지통시간。결과관찰조치료후적총유효솔체90%，현저고우대조조치료후적총유효솔（73.3%），조간비교，차이구유통계학의의（x2=6.387，P＜0.05）。관찰조적지포시간、결가시간、지통시간균분별위（2.56±1.07）d、（3.23±0.85）d、（5.61±1.07）d，대조조적지포시간、결가시간、지통시간균분별위（4.32±1.12）d、（5.96±1.03）d、（8.93±1.02）d、량조비교구유통계학차이（P＜0.05）。결론주사용복방감초산감연합아석락위치료대상포진급후유신경통구유교호적료효，치득추엄。
Objective To observe the clinical efficacy of acyclovir combined with Glycyrrhizin in treatment of herpes zoster and postherpetic neuralgia. Methods A total of 60 inpatients with herpes zoster and postherpetic neuralgia from January 2013 to January 2014 in our hospital were selected as the research object, randomly divided into observation group (n=30, Glycyrrhizin Combined with acyclovir) and control group (n=30,Glycyrrhizin),the efficiency rate, Blister stop time,the scab time, pain time were compared between two groups after treatment. ResultsThe total effective rate of observation group was 90%, was significantly higher than that of the control group (73.3%) ,the difference was significant between two groups(x2=6.387,P<0.05). The check blister time, scabby time, duration of analgesia in observation group were shorter than the control group,the difference was significant between two groups (P<0.05).ConclusionAcyclovir combined with Glycyrrhizin in treatment of herpes zoster and postherpetic neuralgia have exact effect,and can significantly improve the patient's clinical symptoms, reduce the pain of patients,and it is worth of clinical promotion and application.