CAJ | 학술논문

目的：探讨血液透析与腹膜透析对尿毒症患者在钙、磷代谢的影响。方法从该院2012年12月-2013年12月中接收并治疗的尿毒症患者中随机抽取60例进行回顾性研究和分析，并将所有的研究对象随机性的分为观察组和对照组，每组各30例。观察组采用血液透析治疗，对照组采用腹膜透析，在治疗3个月后，对比两组在0、3个月后以及6个月后的钙、磷变化。结果观察组30例患者中低血钙5例，高血钙4例，低血磷3例；对照组30例患者中低血钙5例，高血钙3例，低血磷4例，组间数据比较差异无统计学意义(P>0.05)。观察组发生高血磷12例，甲状旁腺激素13例，甲状旁腺激素5例；对照组发生高血磷2例，甲状旁腺激素2例，甲状旁腺激素1例，组间数据比较差异具有统计学意义(P<0.05)。结论相对于血液透析而言，腹膜透析在治疗尿毒症患者中，更能有效的控制好患者的钙、磷代谢，同时还能更有效的保护患者的残肾功能。因此，值得临床推广和应用。
목적：탐토혈액투석여복막투석대뇨독증환자재개、린대사적영향。방법종해원2012년12월-2013년12월중접수병치료적뇨독증환자중수궤추취60례진행회고성연구화분석，병장소유적연구대상수궤성적분위관찰조화대조조，매조각30례。관찰조채용혈액투석치료，대조조채용복막투석，재치료3개월후，대비량조재0、3개월후이급6개월후적개、린변화。결과관찰조30례환자중저혈개5례，고혈개4례，저혈린3례；대조조30례환자중저혈개5례，고혈개3례，저혈린4례，조간수거비교차이무통계학의의(P>0.05)。관찰조발생고혈린12례，갑상방선격소13례，갑상방선격소5례；대조조발생고혈린2례，갑상방선격소2례，갑상방선격소1례，조간수거비교차이구유통계학의의(P<0.05)。결론상대우혈액투석이언，복막투석재치료뇨독증환자중，경능유효적공제호환자적개、린대사，동시환능경유효적보호환자적잔신공능。인차，치득림상추엄화응용。
Objective To discuss the influence of hemodialysis and peritoneal dialysis on calcium-phosphorous metabolism in ure-mic patients. Methods A retrospective analysis was done on 60 uremic patients admitted in our hospital between December 2012 to December 2013 who were randomly selected and divided into observation group (n=30) and control group (n=30) in which hemodialysis and peritoneal dialysis were performed respectively for the them. Serum calcium and serum phosphorus levels before treatment, 3 months and 6 months after treatment were recorded in the two groups. Results There were 5 cases of hypocalcemia, 4 cases of hypercalcemia and 3 cases of hypophosphatic in the observation group, while 5 cases of hypocalcemia, 3 cases of hyper-calcemia and 4 cases of hypophosphatic in the control group, and the differences between the two groups were not statistically sig-nificant,P>0.05. There were 12 cases of hyperphosphatemia, 13 cases of parathyroid hormone,5 cases of parathyroid hormone in the observation group, while 2 cases of hyperphosphatemia,2 cases of parathyroid hormone, 1 case of parathyroid hormone in the control group, and the differences between the two groups were statistically significant,P<0.05. Conclusion Compared with hemodialysis, peritoneal dialysis can better control calcium-phosphorous metabolism and protect residual renal function, therefore it is worthy of clinical promotion.