CAJ | 학술논문

利用中国知网、万方、维普、PubMed等数据库，系统检索1949~2014年关于中药“十八反”中人参藜芦反药组合同用的文献，从检索到的文章中剔除综述及临床研究文章，仅选取实验研究类的文章，总结归纳人参藜芦反药组合的适宜条件和禁忌条件。结合现有的实验成果，未能归纳出人参藜芦反药组合的适宜的条件，初步认为人参藜芦反药组合的禁忌条件为：人参藜芦合用，人参相当于临床最大剂量的2~10倍，藜芦相当于临床最大剂量的10~30倍；藜芦为临床最高剂量的一半，而人参为临床剂量的4~8倍；人参与藜芦配伍比例小于100：1；红参配伍黑藜芦，生晒参配伍黑藜芦。人参藜芦入药方式、煎煮时间和复方应用因为相关研究较少或不够全面，未能归纳出禁忌条件。人参藜芦反药组合是否是绝对的配伍禁忌，不能一概而论，宜忌条件也不是固定不变的，单一条件下较难确定某一个条件是宜的条件还是忌的条件，随着多学科、多领域研究的不断深入和发展，宜忌条件也会更加丰富和充实。
이용중국지망、만방、유보、PubMed등수거고，계통검색1949~2014년관우중약“십팔반”중인삼려호반약조합동용적문헌，종검색도적문장중척제종술급림상연구문장，부선취실험연구류적문장，총결귀납인삼려호반약조합적괄의조건화금기조건。결합현유적실험성과，미능귀납출인삼려호반약조합적괄의적조건，초보인위인삼려호반약조합적금기조건위：인삼려호합용，인삼상당우림상최대제량적2~10배，려호상당우림상최대제량적10~30배；려호위림상최고제량적일반，이인삼위림상제량적4~8배；인삼여려호배오비례소우100：1；홍삼배오흑려호，생쇄삼배오흑려호。인삼려호입약방식、전자시간화복방응용인위상관연구교소혹불구전면，미능귀납출금기조건。인삼려호반약조합시부시절대적배오금기，불능일개이론，의기조건야불시고정불변적，단일조건하교난학정모일개조건시의적조건환시기적조건，수착다학과、다영역연구적불단심입화발전，의기조건야회경가봉부화충실。
This article summarized the suitable conditions and contraindicant conditions of antagonism compatibility ginseng and veratrum nigrum from the selected experimental research articles by searching“ginseng and veratrum nigrum compatibility of Chinese medicine Eighteen antagonism” from Wan Fang, CNKI, and VIP database since 1949. There is not enough data to summarize suitable conditions. While the contraindicant conditions are as below:the dose of ginseng is equivalent to the maximum clinical dose of 2~10 times, and the dose of veratrum nigrum is equivalent to clinical maximum dose of 10 ~30 times;the dose of ginseng is equivalent to the maximum clinical dose of 4~8 times, and the dose of veratrum nigrum is equivalent to half clinical maximum;the ratio of ginseng with veratrum nigrum is less than 100:1;red ginseng with black veratrum;ginseng with black veratrum. There are contradictory to each other due to the experimental results. Whether the two herbs are absolute incompatibility or not can not be generalized and improper and proper conditions are relative, under a single condition is difficult to identify a particular condition or conditions suitable or not. With the deepening and developing studies, proper and improper conditions will be more enriched and abundent.