CAJ | 학술논문

目的：???探讨原发性干燥综合征（pSS）伴发萎缩性舌炎的危险因素，及伴发萎缩性舌炎舌乳头萎缩程度的相关危险因素。方法???采集36例pSS患者临床资料，拍摄舌背部高清晰度照片，对舌背舌乳头是否伴发萎缩性舌炎及舌乳头萎缩程度进行评价分级，分析患者的临床表现、主观症状和可提取性核抗原（ENA）酶谱的差别，利用单因素及多因素回归方法分析pSS伴发萎缩性舌炎的危险因素，及伴发萎缩性舌炎舌乳头萎缩程度的相关危险因素。结果???多因素回归分析显示：年龄大于65岁以及抗Ro-52抗体阳性是pSS伴发萎缩性舌炎的危险因素，不同年龄段间舌乳头萎缩程度的差异有统计学意义（P<0.05）。结论???年龄大于65岁及抗Ro-52抗体阳性是pSS伴发萎缩性舌炎的危险因素，pSS伴发萎缩性舌炎舌乳头萎缩程度随年龄增长而加重。
목적：???탐토원발성간조종합정（pSS）반발위축성설염적위험인소，급반발위축성설염설유두위축정도적상관위험인소。방법???채집36례pSS환자림상자료，박섭설배부고청석도조편，대설배설유두시부반발위축성설염급설유두위축정도진행평개분급，분석환자적림상표현、주관증상화가제취성핵항원（ENA）매보적차별，이용단인소급다인소회귀방법분석pSS반발위축성설염적위험인소，급반발위축성설염설유두위축정도적상관위험인소。결과???다인소회귀분석현시：년령대우65세이급항Ro-52항체양성시pSS반발위축성설염적위험인소，불동년령단간설유두위축정도적차이유통계학의의（P<0.05）。결론???년령대우65세급항Ro-52항체양성시pSS반발위축성설염적위험인소，pSS반발위축성설염설유두위축정도수년령증장이가중。
Objective???To?identify?the?independent?risk?factors?of?atrophic?glossitis?and?the?influence?factors?of?atrophic?glossitis?degree?in?primary?Sj?gren’s?syndrome(pSS)?patients.?Methods???The?clinical?data?of?36?cases?of?pSS?patients?were?collected?and?taked?the?tongue?back?photos,?graded?the?level?of?the?atrophy?of?tongue?papillae?on?the?back?of?the?tongue.?Clinical?manifestation,?subjective?symptoms?and?extractable?nuclear?antigens(ENA)?spectrum?were?compared?between?the?pSS?patients?with?atrophic?glossitis?and?without?atrophic?glossitis.?The?risk?factors?that?may?cause?atrophic?glossitis?were?analyzed?by?univariate?and?multivariable?Logistic?regression?analysis?and?chi-square?test.?Results???There?were?18?patients?in?36?pSS?patients(50%)?with?atrophic?glossitis.?Age>65,?and?Ro-52?positive?were?the?risk?factors?of?atrophic?glossitis?occurred?in?patients?with?pSS.?Age>65?affected?the?incidence?of?atrophic?glossitis?degree.?There?was?a?statistically?difference?between?groups(P<0.05).?Conclusion???Atrophic?glossitis?is?a?common?complication?of?pSS.?Age?and?Ro-52?positive?is?risk?factors?affecting?pSS?patients?with?atrophic?glossitis?and?aggravating?atrophic?glossitis.?The?degree?of?atrophic?glossitis?increaseed?with?age?in?pSS?patients.