中华放射肿瘤学杂志
中華放射腫瘤學雜誌
중화방사종류학잡지
CHINESE JOURNAL OF RADIATION ONCOLOGY
2015年
5期
556-559
,共4页
尚东平%李明焕%李延持%吴宪宝%尹勇
尚東平%李明煥%李延持%吳憲寶%尹勇
상동평%리명환%리연지%오헌보%윤용
体层摄影术,X线计算机,四维%图像重建%内靶体积%肺肿瘤/放射疗法
體層攝影術,X線計算機,四維%圖像重建%內靶體積%肺腫瘤/放射療法
체층섭영술,X선계산궤,사유%도상중건%내파체적%폐종류/방사요법
Tomography,X-ray computed,four-dimensional%Imaging reconstruction%Internal target volume%Lung neoplasms/radiotherapy
目的:比较4DCT呼吸周期八分法、四分法与传统十分法重建模式对肺孤立灶靶区构建的影响,探讨八分法、四分法在4DCT模拟定位中的可行性。方法24例肺孤立灶行4DCT扫描,按3种呼吸周期均分法进行图像重建及ITV构建,比较ITV10、ITV8、ITV4大小和中心点位置及三维方向运动度。 Friedman M 法非参数检验差异。结果 ITV10、ITV8、ITV4大小分别为(9.09±12?29)、(9.10±12?47)、(8.98±12?61) cm3(P=0?001),ITV10与ITV8相近(P=0?721),ITV10与ITV4不同(P=0?002)。 ITV10、ITV8、ITV4中心点坐标分别为x轴(12.22±7?71)、(12.23±7?71)、(12.22±7?71)(P=0?668);y轴:(43.30±29?38)、(43.30±29?40)、(43.31±29?39)(P=0?643);z轴:(5.66±3?67)、(5.66±3?67)、(5.66±3?67)(P=0?878)。3种重建模式下肿瘤中心在三维方向的运动度分别为x轴:(0.69±0?56)、(0.69±0?68)、(0.79±0?51) mm (P=0?356);y轴:(3.13±3?78)、(3.13±4?05)、(3.19±4?06) mm (P=0?978);z轴:(1.18±1?31)、(1.03±1?32)、(1.16±1?34) mm (P=0?302)。结论肺孤立灶4DCT模拟定位呼吸周期八分法与十分法重建模式下ITV大小、中心点位置及三维方向的运动度均相近,八分法减少了重建图像的数量和靶区勾画负荷,在4DCT模拟定位中具有可行性。
目的:比較4DCT呼吸週期八分法、四分法與傳統十分法重建模式對肺孤立竈靶區構建的影響,探討八分法、四分法在4DCT模擬定位中的可行性。方法24例肺孤立竈行4DCT掃描,按3種呼吸週期均分法進行圖像重建及ITV構建,比較ITV10、ITV8、ITV4大小和中心點位置及三維方嚮運動度。 Friedman M 法非參數檢驗差異。結果 ITV10、ITV8、ITV4大小分彆為(9.09±12?29)、(9.10±12?47)、(8.98±12?61) cm3(P=0?001),ITV10與ITV8相近(P=0?721),ITV10與ITV4不同(P=0?002)。 ITV10、ITV8、ITV4中心點坐標分彆為x軸(12.22±7?71)、(12.23±7?71)、(12.22±7?71)(P=0?668);y軸:(43.30±29?38)、(43.30±29?40)、(43.31±29?39)(P=0?643);z軸:(5.66±3?67)、(5.66±3?67)、(5.66±3?67)(P=0?878)。3種重建模式下腫瘤中心在三維方嚮的運動度分彆為x軸:(0.69±0?56)、(0.69±0?68)、(0.79±0?51) mm (P=0?356);y軸:(3.13±3?78)、(3.13±4?05)、(3.19±4?06) mm (P=0?978);z軸:(1.18±1?31)、(1.03±1?32)、(1.16±1?34) mm (P=0?302)。結論肺孤立竈4DCT模擬定位呼吸週期八分法與十分法重建模式下ITV大小、中心點位置及三維方嚮的運動度均相近,八分法減少瞭重建圖像的數量和靶區勾畫負荷,在4DCT模擬定位中具有可行性。
목적:비교4DCT호흡주기팔분법、사분법여전통십분법중건모식대폐고립조파구구건적영향,탐토팔분법、사분법재4DCT모의정위중적가행성。방법24례폐고립조행4DCT소묘,안3충호흡주기균분법진행도상중건급ITV구건,비교ITV10、ITV8、ITV4대소화중심점위치급삼유방향운동도。 Friedman M 법비삼수검험차이。결과 ITV10、ITV8、ITV4대소분별위(9.09±12?29)、(9.10±12?47)、(8.98±12?61) cm3(P=0?001),ITV10여ITV8상근(P=0?721),ITV10여ITV4불동(P=0?002)。 ITV10、ITV8、ITV4중심점좌표분별위x축(12.22±7?71)、(12.23±7?71)、(12.22±7?71)(P=0?668);y축:(43.30±29?38)、(43.30±29?40)、(43.31±29?39)(P=0?643);z축:(5.66±3?67)、(5.66±3?67)、(5.66±3?67)(P=0?878)。3충중건모식하종류중심재삼유방향적운동도분별위x축:(0.69±0?56)、(0.69±0?68)、(0.79±0?51) mm (P=0?356);y축:(3.13±3?78)、(3.13±4?05)、(3.19±4?06) mm (P=0?978);z축:(1.18±1?31)、(1.03±1?32)、(1.16±1?34) mm (P=0?302)。결론폐고립조4DCT모의정위호흡주기팔분법여십분법중건모식하ITV대소、중심점위치급삼유방향적운동도균상근,팔분법감소료중건도상적수량화파구구화부하,재4DCT모의정위중구유가행성。
Objective To explore the influence of different reconstruction modes with time?weighted respiratory phases on the internal tumor volume ( ITV) of solitary pulmonary lesion ( SPL) , and to evaluate the feasibilities of 8 and 4 equal time?weighted respiratory phases in 4DCT simulation. Methods 24 patients with SPL underwent 4D scanning. Images were reconstructed with 10, 8 and 4 equal time?weighted phases of the respiratory cycles, respectively. Gross tumor volumes ( GTVs ) were delineated on the three sets of reconstructed images and fused into ITVs, which were ITV10 , ITV8 and ITV4 respectively. The differences of volumes, centroid of the ITVs and motions of GTV centroids in three?dimensional directions were compared. Statistical analysis was performed using the Friedman M test. Results The volumes of ITV10 , ITV8 and ITV4 were (9.09±12?29) cm3,(9.10±12?47) cm3 and (8.98±12?61) cm3(P=0?001), respectively. There were no differences between the volumes of ITV10 and ITV8 after the Bonferroni correction ( P=0?721) , while the opposite between those of ITV10 and ITV4 ( P=0?002 ) . The differences of centroid positions of ITV10, ITV8 and ITV4 in x?, y?and z?axes were all less than 1 mm ((12.22±7?71),(12.23± 7?71),(12.22±7?71),Px =0?668);(43.30±29?38),(43.30±29?40),(43.31±29?39),Py =0?643;(5.66±3?67),(5.66±3?67),(5.66±3?67),Pz=0?878), similar to the motions of GTV centroids in three reconstructed modes ((0.69±0?56),(0.69±0?68),(0.79±0?51) mm,Px=0?356;(3.13±3?78),(3.13± 4?05),(3.19±4?06) mm,Py =0?978;(1.18±1?31),(1.03±1?32),(1.16±1?34) mm,Pz=0?302). Conclusions There were no differences in volumes, centroid positions and motions between ITV10 and ITV8 . The quantity of reconstruction images and GTV delineations according to 8 time?weighted phases were both less than conventional 10 phases. 8 time?weighted respiratory phases mode was feasible in 4DCT simulation for SPL.