CAJ | 학술논문

目的：探讨阿奇霉素配伍红霉素治疗小儿支原体肺炎的临床效果。方法：将91例小儿支原体肺炎患者随机分入观察组（阿奇霉素与红霉素配伍治疗）和对照组（红霉素治疗），观察对比两组患儿经过治疗后的总有效率、平均住院日、退热、止咳天数以及不良反应发生率。结果：观察组患儿总有效率为97．83％，明显高于对照组的84．44％（P ＜0．05）；观察组患儿平均住院天数为9．22±2．41d 、平均退热天数为2．98±1．25d ，平均止咳天数为5．34±1．07d ，均明显低于对照组（P＜0．05）；在不良反应方面，两组在胃肠道不良反应、肝肾功能损害和皮疹反应三方面均无显著性差异（P＞0．05）。结论：阿奇霉素与红霉素配伍治疗小儿支原体肺炎有良好的疗效。
목적：탐토아기매소배오홍매소치료소인지원체폐염적림상효과。방법：장91례소인지원체폐염환자수궤분입관찰조（아기매소여홍매소배오치료）화대조조（홍매소치료），관찰대비량조환인경과치료후적총유효솔、평균주원일、퇴열、지해천수이급불량반응발생솔。결과：관찰조환인총유효솔위97．83％，명현고우대조조적84．44％（P ＜0．05）；관찰조환인평균주원천수위9．22±2．41d 、평균퇴열천수위2．98±1．25d ，평균지해천수위5．34±1．07d ，균명현저우대조조（P＜0．05）；재불량반응방면，량조재위장도불량반응、간신공능손해화피진반응삼방면균무현저성차이（P＞0．05）。결론：아기매소여홍매소배오치료소인지원체폐염유량호적료효。
Objective :To explore the clinical efficacy of Azithromycin with erythromycin in treatment of mycoplasmal pneumonia in children .Methods :91 cases of child mycoplasma pneumonia were randomly divided into observation group (Azithromycin with erythromycin) and control group (erythromycin) ,compared two groups’ ef‐fective rate ,average hospitalization days ,incidence of fever ,cough and adverse reaction after treatment .Results :Azithromycin with erythromycin treatment group’s total effective rate was 97 .83% ,significantly higher than that of 84 .44% in the control group (P < 0 .05) ;the average hospitalization days (9 .22 ± 2 .41) ,the average number of days of fever (2 .98 ± 1 .25) and the average number of days of cough (5 .34 ± 1 .07 ) in the observation group was lower than that in the control group (P< 0 .05) ;in adverse reactions ,two groups in the gastrointestinal adverse re‐action symptoms ,liver and kidney function damage and skin rashes have not statistically significant(P> 0 .05) .Con‐clusion :Azithromycin with erythromycin in treatment of child mycoplasmal pneumonia has good effect .