CAJ | 학술논문

目的：对老年泌尿系感染患者菌群分布及耐药情况进行研究，为临床合理使用抗生素提供参考。方法整群选取该院泌尿外科138例老年感染患者细菌培养及药敏临床资料进行统计分析。结果138例老年泌尿系感染菌群分布：革兰氏阴性杆菌检出94株占68.12%，大肠埃希菌(22.46%)、铜绿假单胞菌(18.12%)及鲍曼不动杆菌(15.22%)分居前三位，革兰氏阳性球菌检出40株占28.99%，真菌检出4株占2.90%；大肠埃希菌、铜绿假单胞菌对头孢类、氨苄西林及耐药均较为严重，亚胺培南、氨曲南、环丙沙星及左旋氧氟沙星对三种革兰氏阴性杆菌均有较好的敏感性；粪肠球菌、金黄色葡萄球菌万古霉素未发现耐药菌株，金黄色葡萄球菌对青霉素G、苯唑西林耐药严重。结论根据药敏试验选择抗生素，合理用药于临床治疗的有效性及耐药菌株的减少有重要的临床意义。
목적：대노년비뇨계감염환자균군분포급내약정황진행연구，위림상합리사용항생소제공삼고。방법정군선취해원비뇨외과138례노년감염환자세균배양급약민림상자료진행통계분석。결과138례노년비뇨계감염균군분포：혁란씨음성간균검출94주점68.12%，대장애희균(22.46%)、동록가단포균(18.12%)급포만불동간균(15.22%)분거전삼위，혁란씨양성구균검출40주점28.99%，진균검출4주점2.90%；대장애희균、동록가단포균대두포류、안변서림급내약균교위엄중，아알배남、안곡남、배병사성급좌선양불사성대삼충혁란씨음성간균균유교호적민감성；분장구균、금황색포도구균만고매소미발현내약균주，금황색포도구균대청매소G、분서서림내약엄중。결론근거약민시험선택항생소，합리용약우림상치료적유효성급내약균주적감소유중요적림상의의。
Objective To study the bacteria of urinary tract infection, to provide a reference for clinical rational use of antibiotics. Methods 138 cases of elderly urology surgery of bacterial culture and drug susceptibility in patients with clinical data for statisti-cal analysis. Results In 138 cases of urinary tract infection pathogens: gram negative bacteria were 94 strains accounted for 68.12%, Escherichia coli (22.46%), Pseudomonas aeruginosa (18.12%) and Bauman Acinetobacter (15.22%) separated the top three, gram positive cocci and 40 strains of fungi were accounted for 28.99%, detection 4 strains accounted for 2.90%;Escherichia coli, Pseudomonas aeruginosa to cephalosporin, ampicillin imipenem, aztreonam, ciprofloxacin and levofloxacin against three gram negative bacilli have good sensitivity; Enterococcus faecalis, Staphylococcus aureus, vancomycin resistant strains were not found, severe Staphylococcus aureus to penicillin G, oxacillin resistance. Conclusion Select antibiotic according to antimicrobial suscepti-bility test. The rational use of drugs has important clinical significance to clinical treatment efficacy and reducing drug resistant strains.