中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2015年
22期
55-56
,共2页
PICU%多脏器功能衰竭综合征%乌司他丁%连续性血液滤过
PICU%多髒器功能衰竭綜閤徵%烏司他丁%連續性血液濾過
PICU%다장기공능쇠갈종합정%오사타정%련속성혈액려과
PICU%Multiple organ dysfunction syndrome%Ulinastatin%Continuous hemofiltration
目的：分析PICU多脏器功能衰竭综合征采用乌司他丁联合连续性血液滤过的临床治疗效果。方法随机选择2013年1月-2014年12月该院PICU收治的70例多脏器功能衰竭患儿作为研究对象，根据不同治疗方法，把70例患儿均分为两组，一组为对照组应用常规治疗与连续性血液滤过治疗，另一组为观察组应用乌司他丁联合连续性血液滤过治疗，比较两组患儿临床治疗效果。结果根据APACHEⅡ进行评分，观察组APACHEⅡ(7.3±1.7)、TNF-α(21.28±7.65)μg/L、TXB2(85.2±33.8)ng/L、BUN(8.0±2.2)mmol/L，各项指标明显优于对照组；观察组住院时间与重症监护室应用时间明显少于对照组，两组对比差异有统计学意义(P<0.05)。结论应用乌司他丁联合连续性血液滤过治疗多脏器功能衰竭临床疗效理想，可以明显减少PICU使用率，值得临床推广应用。
目的：分析PICU多髒器功能衰竭綜閤徵採用烏司他丁聯閤連續性血液濾過的臨床治療效果。方法隨機選擇2013年1月-2014年12月該院PICU收治的70例多髒器功能衰竭患兒作為研究對象，根據不同治療方法，把70例患兒均分為兩組，一組為對照組應用常規治療與連續性血液濾過治療，另一組為觀察組應用烏司他丁聯閤連續性血液濾過治療，比較兩組患兒臨床治療效果。結果根據APACHEⅡ進行評分，觀察組APACHEⅡ(7.3±1.7)、TNF-α(21.28±7.65)μg/L、TXB2(85.2±33.8)ng/L、BUN(8.0±2.2)mmol/L，各項指標明顯優于對照組；觀察組住院時間與重癥鑑護室應用時間明顯少于對照組，兩組對比差異有統計學意義(P<0.05)。結論應用烏司他丁聯閤連續性血液濾過治療多髒器功能衰竭臨床療效理想，可以明顯減少PICU使用率，值得臨床推廣應用。
목적：분석PICU다장기공능쇠갈종합정채용오사타정연합련속성혈액려과적림상치료효과。방법수궤선택2013년1월-2014년12월해원PICU수치적70례다장기공능쇠갈환인작위연구대상，근거불동치료방법，파70례환인균분위량조，일조위대조조응용상규치료여련속성혈액려과치료，령일조위관찰조응용오사타정연합련속성혈액려과치료，비교량조환인림상치료효과。결과근거APACHEⅡ진행평분，관찰조APACHEⅡ(7.3±1.7)、TNF-α(21.28±7.65)μg/L、TXB2(85.2±33.8)ng/L、BUN(8.0±2.2)mmol/L，각항지표명현우우대조조；관찰조주원시간여중증감호실응용시간명현소우대조조，량조대비차이유통계학의의(P<0.05)。결론응용오사타정연합련속성혈액려과치료다장기공능쇠갈림상료효이상，가이명현감소PICU사용솔，치득림상추엄응용。
Objective To analyze the clinical effect of ulinastatin combined with continuous hemofiltration in the treatment of mul-tiple organ dysfunction syndrome in PICU. Methods 70 patients with multiple organ dysfunction syndrome admitted in PICU of our hospital during January 2013 and December 2014 were selected as the research object and divided, according to different treat-ment methods, into control group using routine treatment combined with continuous hemofiltration, and observation group adopting ulinastatin combined with continuous hemofiltration. The efficacies of the two groups were compared. Results According to A-PACHE II, APACHEII, TNF-α, TXB2, BUN in the observation group were (7.3±1.7),(21.28±7.65)μg/L,(85.2±33.8)ng/L,(8.0±2.2)mmol/L, respectively, which were superior to those in the control group; the hospitalization time and ICU stay of the observa-tion group were less than those of the control group. The differences above were statistically significant (P<0.05). Conclusion Uli-nastatin combined with continuous hemofiltration in the treatment of multiple organ dysfunction syndrome in PICU is worth promo-tion due to its shorter ICU stay and other good effects.
