中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2015年
15期
67-69,94
,共4页
桂枝芍药知母汤%独活寄生汤%类风湿性关节炎%西医治疗%不良反应
桂枝芍藥知母湯%獨活寄生湯%類風濕性關節炎%西醫治療%不良反應
계지작약지모탕%독활기생탕%류풍습성관절염%서의치료%불량반응
Guizhishaoyaozhimu decoction%Duhuojisheng decoction%Rheumatoid arthritis%Treatment%Adverse reaction
目的：探讨桂枝芍药知母汤合独活寄生汤治疗类风湿性关节炎78例临床的疗效。方法选取2013年10月～2014年12月我院就诊的类风湿性关节炎155例，所有患者随机分为观察组78例及对照组77例。观察两组患者的临床疗效，两组患者治疗前后的症状，体征积分，血沉（ESR）、C反应蛋白（CRP）、血小板体积（MPV）、血小板分布宽度（PDW）及出现的不良反应情况。结果观察组患者的临床总有效率为92.31%，明显高于对照组的80.52%，两组比较差异有统计学意义（P＜0.05）。两组患者治疗后的关节疼痛度，关节压痛程度，关节肿胀度，晨僵时间及关节功能皆明显高于治疗前，差异有统计学意义（P＜0.05）。观察组治疗后节疼痛度，关节压痛程度，关节肿胀度，晨僵时间及关节功能得分等指标明显高于对照组，两组比较，差异有统计学意义（P＜0.05）。两组患者治疗后的ESR、CRP、MPV、PDW皆明显低于治疗前，差异有统计学意义（P＜0.05）。观察组治疗后ESR、CRP、MPV、PDW等指标明显低于对照组，两组比较差异有统计学意义（P＜0.05）。结论桂枝芍药知母汤合独活寄生汤治疗类风湿性关节炎临床疗效显著，明显减少不良反应，值得临床推广应用。
目的：探討桂枝芍藥知母湯閤獨活寄生湯治療類風濕性關節炎78例臨床的療效。方法選取2013年10月～2014年12月我院就診的類風濕性關節炎155例，所有患者隨機分為觀察組78例及對照組77例。觀察兩組患者的臨床療效，兩組患者治療前後的癥狀，體徵積分，血沉（ESR）、C反應蛋白（CRP）、血小闆體積（MPV）、血小闆分佈寬度（PDW）及齣現的不良反應情況。結果觀察組患者的臨床總有效率為92.31%，明顯高于對照組的80.52%，兩組比較差異有統計學意義（P＜0.05）。兩組患者治療後的關節疼痛度，關節壓痛程度，關節腫脹度，晨僵時間及關節功能皆明顯高于治療前，差異有統計學意義（P＜0.05）。觀察組治療後節疼痛度，關節壓痛程度，關節腫脹度，晨僵時間及關節功能得分等指標明顯高于對照組，兩組比較，差異有統計學意義（P＜0.05）。兩組患者治療後的ESR、CRP、MPV、PDW皆明顯低于治療前，差異有統計學意義（P＜0.05）。觀察組治療後ESR、CRP、MPV、PDW等指標明顯低于對照組，兩組比較差異有統計學意義（P＜0.05）。結論桂枝芍藥知母湯閤獨活寄生湯治療類風濕性關節炎臨床療效顯著，明顯減少不良反應，值得臨床推廣應用。
목적：탐토계지작약지모탕합독활기생탕치료류풍습성관절염78례림상적료효。방법선취2013년10월～2014년12월아원취진적류풍습성관절염155례，소유환자수궤분위관찰조78례급대조조77례。관찰량조환자적림상료효，량조환자치료전후적증상，체정적분，혈침（ESR）、C반응단백（CRP）、혈소판체적（MPV）、혈소판분포관도（PDW）급출현적불량반응정황。결과관찰조환자적림상총유효솔위92.31%，명현고우대조조적80.52%，량조비교차이유통계학의의（P＜0.05）。량조환자치료후적관절동통도，관절압통정도，관절종창도，신강시간급관절공능개명현고우치료전，차이유통계학의의（P＜0.05）。관찰조치료후절동통도，관절압통정도，관절종창도，신강시간급관절공능득분등지표명현고우대조조，량조비교，차이유통계학의의（P＜0.05）。량조환자치료후적ESR、CRP、MPV、PDW개명현저우치료전，차이유통계학의의（P＜0.05）。관찰조치료후ESR、CRP、MPV、PDW등지표명현저우대조조，량조비교차이유통계학의의（P＜0.05）。결론계지작약지모탕합독활기생탕치료류풍습성관절염림상료효현저，명현감소불량반응，치득림상추엄응용。
Objective To explore the clinical observation of 78 cases of parasitic decoction in the treatment of rheumatoid arthritis Guizhishaoyaozhimu decoction and Angelica. Methods155 patients with rheumatoid arthritis from October 2013 to December 2014 were randomly divided into observation group and control group with 77 cases and 78 cases.Observe the clinical efficacy of the two groups of patients and to observe the two groups before and after treatment in patients with symptoms and signs of integration, erythrocyte sedimentation rate (ESR),and C-reactive protein (CRP) and platelet volume (MPV),platelet distribution width (PDW) and adverse reactions were all observed and compared.Results The clinical total effective rate of observation group was 92.31%,significantly higher than that of the control group (80.52%),the difference between the two groups was significant (P<0.05).After treatment,the patients in the two groups of joint pain,joint tenderness,swelling degree,time of morning stiffness and joint function were all significantly higher than that in the treatment,the difference was significant (P<0.05).Observe group after treatment,the degree of joint pain,joint tenderness, swelling degree,time of morning stiffness and joint function score index was significantly higher than that of the control group,the two groups, significant difference (P<0.05).The two groups of patients after treatment CRP,MPV,ESR,PDW were significantly lower than before treatment,the difference was significant (P<0.05).ESR,MPV,CRP,PDW and other indicators of the observation group were significantly lower than those in the control group,the difference was significant (P<0.05).Conclusion Guizhi Shaoyao Zhimu decoction combined with angelica parasitic Decoction in the treatment of rheumatoid joint inflammatory disease clinical curative effect significantly,significantly reduced adverse reactions,it is worthy of clinical application.
