中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2015年
22期
17-18
,共2页
低分子肝素%关节置换%血液流变%凝血
低分子肝素%關節置換%血液流變%凝血
저분자간소%관절치환%혈액류변%응혈
Low molecular heparin%Joint replacement%Blood rheology%Blood coagulation
目的：探讨并分析在全麻下低分子肝素对关节置换术术中血液流变学及凝血功能的影响，并对其临床价值进行评价。方法随机选取该院2012年7月-2013年11月期间收治的60例需行关节置换术的患者，采用随机分组的方式，将患者平均分成观察组和对照组，对照组采取常规处理，包括术前肌注肌注鲁米那钠、托品等，常规建立静脉通道与生命体征检测等，在此基础上对观察组患者行低分子肝素处理。对术中的流血量、输液量和手术时间做好详细的记录。结果与对照组相比，观察组患者在注药后1 h和2 h的血沉方程K值、血还原粘度、全血粘度、RBC电泳指数和RBC聚集指数都要低得多，差异有统计学意义(P<0.05)，术中手术时间、输液量和失血量两组患者，差异无统计学意义(P>0.05)。结论在患者全麻状态下使用低分子肝素能够有效的提高关节置换术术中血液流变学的状态，并且手术安全有效，值得借鉴并推广。
目的：探討併分析在全痳下低分子肝素對關節置換術術中血液流變學及凝血功能的影響，併對其臨床價值進行評價。方法隨機選取該院2012年7月-2013年11月期間收治的60例需行關節置換術的患者，採用隨機分組的方式，將患者平均分成觀察組和對照組，對照組採取常規處理，包括術前肌註肌註魯米那鈉、託品等，常規建立靜脈通道與生命體徵檢測等，在此基礎上對觀察組患者行低分子肝素處理。對術中的流血量、輸液量和手術時間做好詳細的記錄。結果與對照組相比，觀察組患者在註藥後1 h和2 h的血沉方程K值、血還原粘度、全血粘度、RBC電泳指數和RBC聚集指數都要低得多，差異有統計學意義(P<0.05)，術中手術時間、輸液量和失血量兩組患者，差異無統計學意義(P>0.05)。結論在患者全痳狀態下使用低分子肝素能夠有效的提高關節置換術術中血液流變學的狀態，併且手術安全有效，值得藉鑒併推廣。
목적：탐토병분석재전마하저분자간소대관절치환술술중혈액류변학급응혈공능적영향，병대기림상개치진행평개。방법수궤선취해원2012년7월-2013년11월기간수치적60례수행관절치환술적환자，채용수궤분조적방식，장환자평균분성관찰조화대조조，대조조채취상규처리，포괄술전기주기주로미나납、탁품등，상규건립정맥통도여생명체정검측등，재차기출상대관찰조환자행저분자간소처리。대술중적류혈량、수액량화수술시간주호상세적기록。결과여대조조상비，관찰조환자재주약후1 h화2 h적혈침방정K치、혈환원점도、전혈점도、RBC전영지수화RBC취집지수도요저득다，차이유통계학의의(P<0.05)，술중수술시간、수액량화실혈량량조환자，차이무통계학의의(P>0.05)。결론재환자전마상태하사용저분자간소능구유효적제고관절치환술술중혈액류변학적상태，병차수술안전유효，치득차감병추엄。
Objective To study and analyze the effect of low molecular heparin to intraoperatie blood rheology and coagulation in patients with joint replacement under general anesthesia and evaluate its clinical value. Methods From July 2012 to November 2013 selected 50 patients who required joint replacement in our hospital. According to the method of random grouping, the pa-tients were divided into observation group and control group on average. The control group take normal processing, including pre-operative muscle intramuscular injection of sodium luminal and atropine, with conventional intravenous and vital signs, etc. On this basis, patients in the observation group accept low molecular heparin treatment. Collect the amount of bleeding in the operation, operation time and quantity of the infusion to do detailed records. Results Compared with control group, the observation group of patients after drug 1 h and 2 h of blood sedimentation equation K value, blood reduction viscosity, whole blood viscosity, RBC electrophoresis index and RBC aggregation index were much lower (P<0.05), and the differences of the amount of intraoperative operative time, transfusion and blood loss of the two group had no significant statistical significance (P>0.05). Conclusion Using low molecular heparin in patients with general anesthesia condition can effectively improve the state of hemorheology in joint re-placement surgery, and surgery is safe and effective, and it is worth reference and promotion.
