中国执业药师
中國執業藥師
중국집업약사
CHINA LICENSED PHARMACIST
2015年
9期
55-56
,共2页
喷他佐辛注射液%高血压样症状%不良反应
噴他佐辛註射液%高血壓樣癥狀%不良反應
분타좌신주사액%고혈압양증상%불량반응
Pentazocine Injection%Hypertension-like Symptoms%Adverse Reaction
1例71岁女性患者因多发脊柱骨折入院，住院期间给予喷他佐辛注射液30 mg，im对症治疗，约5 min后出现高血压样症状，血压156/95 mmHg ，对症治疗后缓解。考虑为喷他佐辛引起的不良反应，该药对心血管系统可能存在“双向效应”，相应物质基础可能分别为组胺和儿茶酚胺。提醒临床医师在使用喷他佐辛时，需密切关注其对血压的“双向效应”，对症处理时宜选择速效、短效的降压药。
1例71歲女性患者因多髮脊柱骨摺入院，住院期間給予噴他佐辛註射液30 mg，im對癥治療，約5 min後齣現高血壓樣癥狀，血壓156/95 mmHg ，對癥治療後緩解。攷慮為噴他佐辛引起的不良反應，該藥對心血管繫統可能存在“雙嚮效應”，相應物質基礎可能分彆為組胺和兒茶酚胺。提醒臨床醫師在使用噴他佐辛時，需密切關註其對血壓的“雙嚮效應”，對癥處理時宜選擇速效、短效的降壓藥。
1례71세녀성환자인다발척주골절입원，주원기간급여분타좌신주사액30 mg，im대증치료，약5 min후출현고혈압양증상，혈압156/95 mmHg ，대증치료후완해。고필위분타좌신인기적불량반응，해약대심혈관계통가능존재“쌍향효응”，상응물질기출가능분별위조알화인다분알。제성림상의사재사용분타좌신시，수밀절관주기대혈압적“쌍향효응”，대증처리시의선택속효、단효적강압약。
A 71-year-old female patient was hospitalized for multiple spine fracture . Pentazocine ( 30 mg , im ) was given for the treatment . Hypertension symptoms occurred 5 minutes after the medication with BP 156/95 mmHg . The symptoms were released after the treatment and were considered as the adverse reactions induced by pentazocine . Pentazocine may have double-effects on cardiovascular system and histamine and catecholamine may be the related substances . Clinical physicians should monitor the double-effects on blood pressure when using penta-zocine and choose quick and short-acting hypotensive drugs for the treatment .
