CAJ | 학술논문

目的：调查了解我院住院患者中质子泵抑制剂使用的合理性。方法：制定我院质子泵抑制剂的临床应用指导原则，随机抽取本院2014年1-12月的住院患者病历744份，依据指导原则进行分析评价，并对不合理的处方进行讨论。结果：744份病历中，不合理病历共320份，占43.01%，不合理的原因分别是给药途径、无使用指征、疗程偏长、用法用量、重复用药和药物相互作用，所占比例依次为33.75%，30.62%，16.25%，10.00%，5.00%，4.38%。结论：质子泵抑制剂在我院临床应用上不甚合理，为了节约医疗成本和进一步提高用药水平，还需要考虑给药途径、使用指征、疗程偏长、用法用量、重复用药和药物相互作用等多方面的因素。
목적：조사료해아원주원환자중질자빙억제제사용적합이성。방법：제정아원질자빙억제제적림상응용지도원칙，수궤추취본원2014년1-12월적주원환자병력744빈，의거지도원칙진행분석평개，병대불합리적처방진행토론。결과：744빈병력중，불합리병력공320빈，점43.01%，불합리적원인분별시급약도경、무사용지정、료정편장、용법용량、중복용약화약물상호작용，소점비례의차위33.75%，30.62%，16.25%，10.00%，5.00%，4.38%。결론：질자빙억제제재아원림상응용상불심합리，위료절약의료성본화진일보제고용약수평，환수요고필급약도경、사용지정、료정편장、용법용량、중복용약화약물상호작용등다방면적인소。
Objective:To investigate the rationality of the use of proton pump inhibitors ( PPIs ) in the inpatients of our hospital . Methods:The guiding principle of clinical application of proton pump inhibitors in our hospital was established . About 744 medical records of inpatients were randomly selected from January to December in 2014 . The analysis and evaluation were made according to the guiding principle and the unreasonable prescriptions were discussed . Results:Of 744 medical records , 320 of them was found unreasonable , accounting for 43 . 01%, which mainly reflected in the following aspects such as the route of administration , non-indicated use of drugs , long course of treatment, usage and dosage, repeated use of drugs and drug interactions, with the proportion of 33.75%, 30 . 62%, 16 . 25%, 10 . 00%, 5 . 00% and 4 . 38% respectively . Conclusion:The clinical use of PPI in our hospital was irrational . In order to reduce the medical cost and further improve the level of rational drug use , considerations should be given to the above mentioned factors .