CAJ | 학술논문

目的：目的探讨炎琥宁联合干扰素泵吸治疗儿童手足口病的有效性。方法选取首都儿科研究所附属儿童医院门诊确诊并治疗的手足口病患儿55例进行观察,患儿按照数字表法随机分为两组：①治疗组28例：予以炎琥宁(10mg/kg,静点,每日1次),并雾化吸入用重组人干扰素a-1b注射液(2μg/kg,每日1次)。②对照组27例：予以炎琥宁(10mg/kg,静点,每日1次)。患儿分别予治疗后第1、2、3、7天随访。结果显效率：治疗组中为53.6％,对照组为22.2％,两组间差异有显著性。结论炎琥宁联合干扰素泵吸治疗儿童手足口病比可以替代静脉输注炎琥宁。
목적：목적탐토염호저연합간우소빙흡치료인동수족구병적유효성。방법선취수도인과연구소부속인동의원문진학진병치료적수족구병환인55례진행관찰,환인안조수자표법수궤분위량조：①치료조28례：여이염호저(10mg/kg,정점,매일1차),병무화흡입용중조인간우소a-1b주사액(2μg/kg,매일1차)。②대조조27례：여이염호저(10mg/kg,정점,매일1차)。환인분별여치료후제1、2、3、7천수방。결과현효솔：치료조중위53.6％,대조조위22.2％,량조간차이유현저성。결론염호저연합간우소빙흡치료인동수족구병비가이체대정맥수주염호저。
Objective To evaluate and explore the efficacy and safety of Yanhuning injection with interferon inhala-tion in treating hand foot and mouth disease ( HFMD) children. Method In this trial, 55 children diagnosed of HFMD and received treatment in Capital Institute of Pediatrics Affiliated Children’ s Hospital aged 1 to 4 years were randomly divided into treatment group ( n=28 ) which received Yanhuning injection with interferon inhalation and control group(n=27)which received Yanhuning injection 1 time daily for 7 days follow-up. The treatment effect was divided intothe significant effect, the normal effect and the invalid effect. Result The significant rate of the treat-ment group was 53. 6% and the control group was 22. 2%. There was significant differences between two groups(P<0. 05). The normal effect or invalid effect of treatment did not differ significantly between the two groups. Conclusion Children with HFMD may benefit from Yanhuning injection with interferon inhalation treatment as com-pared with Yanhuning injection. No significant adverse drug reactions are observed for the two groups.