CAJ | 학술논문

目的：探讨声脉冲辐射力成像(acoustic radiation force impulse,ARFI)技术与彩色多普勒血流显像(color Doppler flow imaging,CDFI)联合诊断肝移植术后急性排异反应的应用价值。方法采用回顾性研究方法,对在我院进行肝组织活检并经病理确诊为急性排异反应的58例肝移植患者行常规超声检查及 CDFI、ARFI 检查,主要观察指标为移植肝前后径、门静脉主干平均流速、肝静脉的频谱波形及剪切波速度,并与30例正常人结果进行对照分析。结果与正常对照组比较,急性排异组肝前后径增大,门静脉主干流速减低,肝静脉三相波形消失以及剪切波速度加快,且差异有统计学意义(P =0.000,0.000,0.007,0.000),4个指标与分组之间的相关系数分别为0.478,0.557,0.286,0.483；利用上述4个指标综合诊断肝移植术后急性排异的 ROC 曲线下面积是0.914。结论利用 ARFI 和 CDFI 共同诊断肝移植术后出现急性排异反应具有较高的准确性。
목적：탐토성맥충복사력성상(acoustic radiation force impulse,ARFI)기술여채색다보륵혈류현상(color Doppler flow imaging,CDFI)연합진단간이식술후급성배이반응적응용개치。방법채용회고성연구방법,대재아원진행간조직활검병경병리학진위급성배이반응적58례간이식환자행상규초성검사급 CDFI、ARFI 검사,주요관찰지표위이식간전후경、문정맥주간평균류속、간정맥적빈보파형급전절파속도,병여30례정상인결과진행대조분석。결과여정상대조조비교,급성배이조간전후경증대,문정맥주간류속감저,간정맥삼상파형소실이급전절파속도가쾌,차차이유통계학의의(P =0.000,0.000,0.007,0.000),4개지표여분조지간적상관계수분별위0.478,0.557,0.286,0.483；이용상술4개지표종합진단간이식술후급성배이적 ROC 곡선하면적시0.914。결론이용 ARFI 화 CDFI 공동진단간이식술후출현급성배이반응구유교고적준학성。
Objective To investigate the value of acoustic radiation force impulse (ARFI)and color Doppler flow imaging (CDFI)in the diagnostic of acute rejection (AR)after liver transplantation.Methods B mode ultrasound,CDFI and ARFI exams were performed on fifty-eight patients who was diagnosed with AR through liver biopsy in our hospital.The liver allograft size,mean velocity of portal vein,hepatic vein spectrum waveform and shear-wave velocity were obtained and compared with the results of 30 healthy subjects as control group.Results Compare to control group,the AR group had a significant increase in liver allograft,decrease in mean velocity of portal vein,the elimination of triphasic wave of hepatic vein,and a significant increase in shear-wave velocity (P =0.000,0.000,0.007,0.000,respectively).The correlation coefficient between four criteria and grouping was 0.478,0.557,0.286,0.483,respectively.The area under ROC curves for diagnosing AR using the four criterias mentioned above was 0.914.Conclusions Combination of CDFI and ARFI in diagnosing of AR after liver transplantation has higher sensitivity and accuracy.