蚌埠医学院学报
蚌埠醫學院學報
방부의학원학보
ACTA ACADEMIAE MEDICINAE BENGBU
2015年
9期
1247-1249
,共3页
烧伤%细菌感染%耐药%革兰阳性菌%革兰阴性菌
燒傷%細菌感染%耐藥%革蘭暘性菌%革蘭陰性菌
소상%세균감염%내약%혁란양성균%혁란음성균
burn%bacteria infection%drug resistance%gram positive bacteria%gram negative bacteria
目的：：探讨烧伤患者创面细菌感染的分布特点及耐药性。方法：对326例烧伤患者不同阶段的创面分泌物进行多次采集并进行细菌培养和鉴定,对革兰阴性及阳性菌的耐药性进行检测。结果：检出革兰阴性杆菌219株,病原菌的69.52%,比例最高的为铜绿假单胞菌(25.71%)；革兰阳性球菌占25.08%,比例最高的为金黄色葡萄球菌(9.52%)。铜绿假单胞菌对复方磺胺甲口恶唑的耐药率最高(97.45%),对阿米卡星的耐药率最低(21.12%)；鲍曼不动杆菌对氨曲南和头孢噻肟的耐药率最高(均为100.00%),对头孢哌酮/舒巴坦的耐药率最低(29.59%)；大肠埃希菌对复方磺胺甲口恶唑的耐药率最高(79.48%),对亚胺培南的耐药率最低(0.00%)；肺炎克雷伯菌对哌拉西林的耐药率最高(88.26%),对美罗培南的耐药率最低(1.42%)。金黄色葡萄球菌和表皮葡萄球菌对青霉素的耐药率均最高(94.62%,96.37%),对利奈唑胺和万古霉素的耐药率最低(均为0.00%)。结论：烧伤患者创面感染的病原菌类型主要为革兰阴性菌,并且耐药现象日益严重,临床上应掌握病原菌的分布特点并及时监测耐药情况,以指导合理用药,控制再次感染。
目的：：探討燒傷患者創麵細菌感染的分佈特點及耐藥性。方法：對326例燒傷患者不同階段的創麵分泌物進行多次採集併進行細菌培養和鑒定,對革蘭陰性及暘性菌的耐藥性進行檢測。結果：檢齣革蘭陰性桿菌219株,病原菌的69.52%,比例最高的為銅綠假單胞菌(25.71%)；革蘭暘性毬菌佔25.08%,比例最高的為金黃色葡萄毬菌(9.52%)。銅綠假單胞菌對複方磺胺甲口噁唑的耐藥率最高(97.45%),對阿米卡星的耐藥率最低(21.12%)；鮑曼不動桿菌對氨麯南和頭孢噻肟的耐藥率最高(均為100.00%),對頭孢哌酮/舒巴坦的耐藥率最低(29.59%)；大腸埃希菌對複方磺胺甲口噁唑的耐藥率最高(79.48%),對亞胺培南的耐藥率最低(0.00%)；肺炎剋雷伯菌對哌拉西林的耐藥率最高(88.26%),對美囉培南的耐藥率最低(1.42%)。金黃色葡萄毬菌和錶皮葡萄毬菌對青黴素的耐藥率均最高(94.62%,96.37%),對利奈唑胺和萬古黴素的耐藥率最低(均為0.00%)。結論：燒傷患者創麵感染的病原菌類型主要為革蘭陰性菌,併且耐藥現象日益嚴重,臨床上應掌握病原菌的分佈特點併及時鑑測耐藥情況,以指導閤理用藥,控製再次感染。
목적：：탐토소상환자창면세균감염적분포특점급내약성。방법：대326례소상환자불동계단적창면분비물진행다차채집병진행세균배양화감정,대혁란음성급양성균적내약성진행검측。결과：검출혁란음성간균219주,병원균적69.52%,비례최고적위동록가단포균(25.71%)；혁란양성구균점25.08%,비례최고적위금황색포도구균(9.52%)。동록가단포균대복방광알갑구악서적내약솔최고(97.45%),대아미잡성적내약솔최저(21.12%)；포만불동간균대안곡남화두포새우적내약솔최고(균위100.00%),대두포고동/서파탄적내약솔최저(29.59%)；대장애희균대복방광알갑구악서적내약솔최고(79.48%),대아알배남적내약솔최저(0.00%)；폐염극뢰백균대고랍서림적내약솔최고(88.26%),대미라배남적내약솔최저(1.42%)。금황색포도구균화표피포도구균대청매소적내약솔균최고(94.62%,96.37%),대리내서알화만고매소적내약솔최저(균위0.00%)。결론：소상환자창면감염적병원균류형주요위혁란음성균,병차내약현상일익엄중,림상상응장악병원균적분포특점병급시감측내약정황,이지도합리용약,공제재차감염。
Objective:To investigate the bacterial infection distribution and drug resistance in burn wound. Methods:The bacteria from the wound secretion of different stages in 326 burn patients were cultured and identified. The drug resistance of gram negative and gram positive bacteria were detected. Results:The gram negative bacilli accounted for 69. 52%(219 trains) of 315 strains of pathogenic bacteria,the proportion of pseudomonas aeruginosa was the highest(25. 71%). The gram positive cocci accounted for 25. 08%,the proportion of staphylococcus aureus was the highest(9. 52%). The drug resistance rates of pseudomonas aeruginosa to cotrimoxazole and amikacin were the highest(97. 45%) and lowest(21. 12%),respectively. The drug resistance rates of bauman acinetobacter to aztreonam & cefotaxime and cefoperazone/sulbactam were the highest(100. 00%) and lowest(29. 59%),respectively. The drug resistance rates of Escherichia coli to cotrimoxazole and imipenem were the highest(79. 48%) and lowest(0. 00%),respectively. The drug resistance rates of klebsiella pneumoniae to piperacillin and meropenem were the highest(88. 26%) and lowest(1. 42%), respectively. The drug resistance rates of staphylococcus aureus&Staphylococcus aureus to penicillin and linezolid&vancomycin were the highest(94. 62%& 96. 37%) and lowermost(0. 00% and 0. 00%),respectively. Conclusions:The Gram-negative bacteria is mainly pathogenic bacteria in burn wound infection,the drug resistance of which increases. Knowing the distribution characteristics of pathogenic bacteria and timely monitoring its drug resistance can guide the rational drug use and control infection again.
