CAJ | 학술논문

目的：探讨生物活性透明质酸牙膏刷牙治疗牙龈炎的疗效。方法按就诊顺序，将牙龈炎患者40例分为实验组和对照组，各20例。实验组采用含有2%生物活性透明质酸的牙膏刷牙，2次/d，观察牙龈炎的情况；对照组采用普通牙膏刷牙，2次/d，观察牙龈炎的情况；比较两组治疗5天后症状和体征改善情况。结果（1）症状改善情况：实验组显效5例，有效15例，无效0例，总有效率100%，对照组显效0例，有效0例，无效20例，总有效率0%，差异有统计学意义（P＜0.05）。（2）临床体征改善情况：实验组显效18例，有效2例，无效0例，总有效率100%，对照组显效0例，有效0例，无效20例，总有效率0%，差异有统计学意义（P＜0.05）。结论生物活性透明质酸牙膏刷牙治疗牙龈炎疗效显著，值得社区普及推广。
목적：탐토생물활성투명질산아고쇄아치료아간염적료효。방법안취진순서，장아간염환자40례분위실험조화대조조，각20례。실험조채용함유2%생물활성투명질산적아고쇄아，2차/d，관찰아간염적정황；대조조채용보통아고쇄아，2차/d，관찰아간염적정황；비교량조치료5천후증상화체정개선정황。결과（1）증상개선정황：실험조현효5례，유효15례，무효0례，총유효솔100%，대조조현효0례，유효0례，무효20례，총유효솔0%，차이유통계학의의（P＜0.05）。（2）림상체정개선정황：실험조현효18례，유효2례，무효0례，총유효솔100%，대조조현효0례，유효0례，무효20례，총유효솔0%，차이유통계학의의（P＜0.05）。결론생물활성투명질산아고쇄아치료아간염료효현저，치득사구보급추엄。
Objective The aim of this study was to investigate therapeutic effect of topical application of bioactive hyaluronic acid for treatment of gingivitis.Methods 40 patients were divided into two groups. Experimental group has 20 patients while control group has 20 patients.Toothpast containing 2% bioactive hyaluronic acid was used in the experimental group.Then, the symptoms and signs of gingivitis was monitored.A regular toothpast was used in the control group.Results (1)Clinical symptom improvement, 5 patients in experimental group achieved significantly improvement.15 patients in experimental group achieved improvement.While, in control group, no patients achieved improvement(P<0.05).(2)Clinical sign improvement: 18 patients in experimental group achieved significantly improvement.2 patients in experimental group achieved improvement.While, in control group, no patients achieved improvement(P<0.05).Conclusion Topical application of 2% bioactive hyaluronic acid through tooth brushing significantly inhibits the symptoms and signs of gingivitis, indicating its therapeutic role in prevention and treatment of periodental diseases.