CAJ | 학술논문

目的：探讨全数字化乳腺X线摄影（fullifeld digital mammography，FFDM）及彩色多普勒血流成像（color Dopplerlfow imaging，CDFI）对乳腺癌的诊断价值，并分析FFDM及CDFI特征与乳腺良/恶性病变的关系，为提高乳腺癌患者的早期诊断准确率提供依据。方法选取2010年1月至2014年7月本院经手术病理证实且于术前行FFDM及CDFI检查的435例乳腺癌患者和239例乳腺良性肿瘤患者为研究对象。以病理检查结果作为金标准，分别计算FFDM、CDFI及其联合应用对乳腺癌诊断的灵敏度、特异度、正确指数、阳性预测值和阴性预测值，并比较三种方法的诊断结果，进一步分析FFDM及CDFI特征与乳腺良/恶性病变的关系。结果 FFDM对乳腺癌诊断的灵敏度、特异度及正确指数均高于CDFI，FFDM＋CDFI诊断的灵敏度、特异度及正确指数均高于单独诊断。FFDM、CDFI、病理检查结果均一致的患者，乳腺良/恶性病变的FFDM及CDFI特征分析显示，乳腺癌患者的肿块形态不规则、边缘呈毛刺及浸润、结构扭曲及钙化的比例均高于乳腺良性肿瘤（P＜0.05）；乳腺癌患者的肿块形态不规则、边缘呈毛刺、浸润及小分叶、回声不均匀、钙化、血流信号2～4级的比例均高于乳腺良性肿瘤（P＜0.05）。结论 FFDM在乳腺癌的诊断中具有较高的应用价值，FFDM与CDFI联合检查对乳腺癌及不同临床分期乳腺癌的诊断均优于单独诊断。乳腺病变中FFDM及CDFI特征对乳腺良/恶性病变的鉴别诊断有一定意义。
목적：탐토전수자화유선X선섭영（fullifeld digital mammography，FFDM）급채색다보륵혈류성상（color Dopplerlfow imaging，CDFI）대유선암적진단개치，병분석FFDM급CDFI특정여유선량/악성병변적관계，위제고유선암환자적조기진단준학솔제공의거。방법선취2010년1월지2014년7월본원경수술병리증실차우술전행FFDM급CDFI검사적435례유선암환자화239례유선량성종류환자위연구대상。이병리검사결과작위금표준，분별계산FFDM、CDFI급기연합응용대유선암진단적령민도、특이도、정학지수、양성예측치화음성예측치，병비교삼충방법적진단결과，진일보분석FFDM급CDFI특정여유선량/악성병변적관계。결과 FFDM대유선암진단적령민도、특이도급정학지수균고우CDFI，FFDM＋CDFI진단적령민도、특이도급정학지수균고우단독진단。FFDM、CDFI、병리검사결과균일치적환자，유선량/악성병변적FFDM급CDFI특정분석현시，유선암환자적종괴형태불규칙、변연정모자급침윤、결구뉴곡급개화적비례균고우유선량성종류（P＜0.05）；유선암환자적종괴형태불규칙、변연정모자、침윤급소분협、회성불균균、개화、혈류신호2～4급적비례균고우유선량성종류（P＜0.05）。결론 FFDM재유선암적진단중구유교고적응용개치，FFDM여CDFI연합검사대유선암급불동림상분기유선암적진단균우우단독진단。유선병변중FFDM급CDFI특정대유선량/악성병변적감별진단유일정의의。
ObjectiveTo research the diagnostic signiifcance of full ifeld digital mammography (FFDM) and color Doppler lfow imaging (CDFI) in patients with female breast disease in Xinjiang region and to analyze the relationship among characteristics of FFDM and CDFI and female breast disease.Method435 patients with breast cancer and 239 patients with breast benign tumor from January 2010 to July 2014 in surgical pathology in our hospital were selected as the research subjects, pathologic examination results as the gold standard, the sensitivity, speciifc, right index, the positive predictive value and negative predictive value were calculated and compared.ResultThe sensitivity, speciifc and accurate index of FFDM were higher than CDFI, combined diagnosis had the higher sensitivity, speciifc and accurate index than the separate diagnosis. The FFDM features of breast cancer, such as, breast shape was irregular shape, mass burr and inifltration, structure distortion and rim calciifcation proportion were higher than breast benign lesions. The CDFI features of breast cancer, such as, breast shape was irregular, margins of burr, inifltration and small leaf, mass uneven echo, calciifcation, blood lfow signal level 2~4 percentage were higher than breast benign lesions.ConclusionFFDM in the diagnosis of patients with breast cancer has a higher value. FFDM combined with CDFI in the diagnosis of breast cancer are superior to single diagnosis in different clinical stages.