中华临床医师杂志（电子版）
中華臨床醫師雜誌（電子版）
중화림상의사잡지（전자판）
CHINESE JOURNAL OF CLINICIANS(ELECTRONIC VERSION)
2015年
16期
3052-3056
,共5页
受精,体外%先天畸形%男方年龄%精液分析%新生儿性别
受精,體外%先天畸形%男方年齡%精液分析%新生兒性彆
수정,체외%선천기형%남방년령%정액분석%신생인성별
Fertilization in vitro%Congenital abnormalities%Paternal age%Semen analysis%Sex ratio
目的：分析男方年龄对于小于38岁妇女进行常规体外受精（IVF）助孕妊娠结局的影响。方法回顾性分析2012年在我中心进行常规IVF助孕治疗的夫妇，选取女方年龄小于38岁，具有正常的基础卵巢储备[卵泡生成激素（FSH）＜12 IU/L和基础窦卵泡数＞8个，排除多囊卵巢综合征患者]的815对夫妇，根据男方年龄分为两组：＜40岁组（n=759）及≥40岁组（n=56），比较两组间男方精液指标、生化妊娠率、临床妊娠率、流产率、活产率、新生儿体重、新生儿性别比的差异。结果男方年龄在22岁至55岁之间时，＜40岁组与≥40岁组男方精液指标无明显差异，生化妊娠率、临床妊娠率、流产率、活产率、新生儿体重、新生儿性别比在两组间存在差异，但没有统计学意义。结论男方年龄在22～55岁之间时，对于小于38岁妇女进行常规IVF助孕妊娠结局没有明显的影响。
目的：分析男方年齡對于小于38歲婦女進行常規體外受精（IVF）助孕妊娠結跼的影響。方法迴顧性分析2012年在我中心進行常規IVF助孕治療的伕婦，選取女方年齡小于38歲，具有正常的基礎卵巢儲備[卵泡生成激素（FSH）＜12 IU/L和基礎竇卵泡數＞8箇，排除多囊卵巢綜閤徵患者]的815對伕婦，根據男方年齡分為兩組：＜40歲組（n=759）及≥40歲組（n=56），比較兩組間男方精液指標、生化妊娠率、臨床妊娠率、流產率、活產率、新生兒體重、新生兒性彆比的差異。結果男方年齡在22歲至55歲之間時，＜40歲組與≥40歲組男方精液指標無明顯差異，生化妊娠率、臨床妊娠率、流產率、活產率、新生兒體重、新生兒性彆比在兩組間存在差異，但沒有統計學意義。結論男方年齡在22～55歲之間時，對于小于38歲婦女進行常規IVF助孕妊娠結跼沒有明顯的影響。
목적：분석남방년령대우소우38세부녀진행상규체외수정（IVF）조잉임신결국적영향。방법회고성분석2012년재아중심진행상규IVF조잉치료적부부，선취녀방년령소우38세，구유정상적기출란소저비[란포생성격소（FSH）＜12 IU/L화기출두란포수＞8개，배제다낭란소종합정환자]적815대부부，근거남방년령분위량조：＜40세조（n=759）급≥40세조（n=56），비교량조간남방정액지표、생화임신솔、림상임신솔、유산솔、활산솔、신생인체중、신생인성별비적차이。결과남방년령재22세지55세지간시，＜40세조여≥40세조남방정액지표무명현차이，생화임신솔、림상임신솔、유산솔、활산솔、신생인체중、신생인성별비재량조간존재차이，단몰유통계학의의。결론남방년령재22～55세지간시，대우소우38세부녀진행상규IVF조잉임신결국몰유명현적영향。
Objective The aim of this study was to assess the effect of paternal age on the reproductive outcome of women<38 years after conventional IVF-ET. Methods Retrospective analysis of 815 couples underwent conventional IVF-ET in our center in 2012, which women were<38 years with normal baseline ovarian reserve testing (FSH<12 IU/L and basal antral follicle count>8, exclude the polycystic ovarian syndrome), base on the paternal age, 815 couples were divided into two groups:<40 years (n=759) and ≥40 years (n=56), we observed the biochemical pregnancy rate, clinical pregnancy rate, abortion rate, live birth rate, neonatal birth weight, birth defects and the sex ratio among newborns in two groups. Results When the paternal age was between 22 and 55 years, there was no significant difference of biochemical pregnancy rate, clinical pregnancy rate, abortion rate, live birth rate, neonatal birth weight, birth defects and the sex ratio among newborns between<40 years and ≥40 years groups. Conclusion When the paternal age is between 22 and 55 years, there is no effect of paternal age on the reproductive outcome of women<38 years after conventional IVF-ET.
