CAJ | 학술논문

目的：探讨短暂性脑缺血发作（TIA）新定义（短暂的局灶性脑或视网膜缺血所致的神经功能障碍，通常持续时间不足1 h，且没有急性梗死的证据）的合理性。方法回顾性分析822例短暂性脑缺血发作住院患者的临床资料。699例（53.65%）接受CT检查，440例（53.65%）接受头颅MRI检查，其中182例（22.14%）同时进行了DWI检查。统计临床症状的持续时间，统计分析TIA症状持续时间与脑CT、MRI及弥散加权成像之间的关系。结果342例患者TIA持续在10 min以内，611例（74.33%）1 h以内，715例患者在3 h以内；778例患者的临床表现在6 h以内。临床症状持续时间与脑T、MRI、CT/MRI、DWI异常率间的联系差异无统计学意义。结论 TIA新定义对于部分患者不适用，TIA传统定义从临床及科研角度考虑可以沿用。
목적：탐토단잠성뇌결혈발작（TIA）신정의（단잠적국조성뇌혹시망막결혈소치적신경공능장애，통상지속시간불족1 h，차몰유급성경사적증거）적합이성。방법회고성분석822례단잠성뇌결혈발작주원환자적림상자료。699례（53.65%）접수CT검사，440례（53.65%）접수두로MRI검사，기중182례（22.14%）동시진행료DWI검사。통계림상증상적지속시간，통계분석TIA증상지속시간여뇌CT、MRI급미산가권성상지간적관계。결과342례환자TIA지속재10 min이내，611례（74.33%）1 h이내，715례환자재3 h이내；778례환자적림상표현재6 h이내。림상증상지속시간여뇌T、MRI、CT/MRI、DWI이상솔간적련계차이무통계학의의。결론 TIA신정의대우부분환자불괄용，TIA전통정의종림상급과연각도고필가이연용。
Objective To discuss the rationality of the new definition of transient ischemic attack (TIA):a brief episode of neurological disfunction caused by focal brain or retinal ischemia, with clinical symptoms typically lasting less than one hour and without evidence of acute infarction. Methods The clinical dataaa pf 822 TIA patients, aged(65.68 ± 14.3), were analyzed retrospectively. The lasting time of clinical symptoms were recorded. 699 cases (85.04) underwent brain CT examination, and 440 cases (53.65%) underwent craniao MRI examination among which 182 cases (22.14%) received DWI examination. The relation of TIA lasting time with brain CT, MRI , and DWI were analyzed. Results The percentages of the duration time of TIA symptoms for less than 10 minutes, 1 hour, 3 hours, and 6 hours were 41.6%, 74%, 87%, and 96% respectively. The case numbers with Ischemic focus found in the CT/MRI/DWI groups were not significantly related with the duration time of TIA symptoms (all P>0.05). Conclusion The new definition of TIA is not valid for some patients with TIA, and it is more reasonable to follow the classic definition.