CAJ | 학술논문

脑室腹膜分流术后，表皮葡萄球菌常在分流管表面粘附聚集形成生物膜，生物膜包裹细菌，可以保护其免受宿主的攻击。由于存在生物膜、抗菌药物耐药、中枢神经系统的血脑屏障等因素，脑室腹膜分流术后表皮葡萄球菌感染的治疗非常困难。此文对脑室腹膜分流术后表皮葡萄球菌感染的易感因素与发生率、发病机制、治疗、预防等方面的进展进行综述。
뇌실복막분류술후，표피포도구균상재분류관표면점부취집형성생물막，생물막포과세균，가이보호기면수숙주적공격。유우존재생물막、항균약물내약、중추신경계통적혈뇌병장등인소，뇌실복막분류술후표피포도구균감염적치료비상곤난。차문대뇌실복막분류술후표피포도구균감염적역감인소여발생솔、발병궤제、치료、예방등방면적진전진행종술。
Staphylococcus epidermidis has the ability to adhere to the surface of shunt tube and to develop the biofilm .It can embed itself in the biofilm so as to escape from the defense of the host .Due to the presence of biofilms , antimicrobial drug resistance , blood brain barrier of central nervous system , the treatment of shunt-related infection caused by Staphylococcus epidermidis is very difficult.This paper reviews the risk factors , prevalence , pathogenesis , treatment and prevention of ventriculoperitoneal shunt-related infections caused by Staphylococcus epidermidis.