CAJ | 학술논문

葡萄糖依赖性促胰岛素释放肽( GIP)可促进β细胞释放胰岛素,但这种作用在肥胖患者中存在缺陷。越来越多的证据表明,GIP在高脂饮食和肥胖、胰岛素抵抗及2型糖尿病之间起桥梁作用。随着GIP在2型糖尿病及肥胖不断深入地研究,为其治疗提供了新思路。
포도당의뢰성촉이도소석방태( GIP)가촉진β세포석방이도소,단저충작용재비반환자중존재결함。월래월다적증거표명,GIP재고지음식화비반、이도소저항급2형당뇨병지간기교량작용。수착GIP재2형당뇨병급비반불단심입지연구,위기치료제공료신사로。
[Summary] Glucose-dependent insulinotropic polypeptide ( GIP) is known to promote the release of insulin fromβcells, but this function suffers from a defect in obese patients. More and more evidences suggest that GIP is the bridge between a high-fat diet, obesity, insulin resistance, and type 2 diabetes. With the deepening of research in GIP in type 2 diabetes and obesity, GIP may provide new ideas for the treatment of type 2 diabetes and obesity.