中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2015年
22期
82-83,85
,共3页
胃痛宁合剂%雷贝拉唑%功能性消化不良上腹痛综合征%疗效观察
胃痛寧閤劑%雷貝拉唑%功能性消化不良上腹痛綜閤徵%療效觀察
위통저합제%뢰패랍서%공능성소화불량상복통종합정%료효관찰
The Weitongning decoction%Bella%Functional dyspepsia upper abdominal pain%Effective observation
目的：观察胃痛宁合剂联合雷贝拉唑治疗功能性消化不良上腹痛综合征的临床疗效。方法：将102例功能性消化不良上腹痛综合征患者随机分为两组，对照组给予常规雷贝拉唑钠肠溶胶囊，20mg/d，早上空腹口服；治疗组在对照组的基础上加服河南中医学院第一附属医院院内制剂——胃痛宁合剂，30mL/次，3次/d口服，两组均治疗15d。观察两组治疗前、后主要临床症状及中医证候积分变化情况。结果：两组组内治疗后与治疗前症状总积分比较，差异具有统计学意义（P<0.05）；治疗后治疗组与对照组症状总积分比较有显著性差异（P<0.05），治疗组明显优于对照组；治疗组与对照组疗效比较有显著性差异（P<0.05），治疗组明显优于对照组。结论：胃痛宁合剂联合雷贝拉唑钠肠溶胶囊和单用雷贝拉唑均可改善功能性消化不良上腹痛综合征的临床症状，但胃痛宁合剂联合雷贝拉唑的疗效优于常规雷贝拉唑治疗。
目的：觀察胃痛寧閤劑聯閤雷貝拉唑治療功能性消化不良上腹痛綜閤徵的臨床療效。方法：將102例功能性消化不良上腹痛綜閤徵患者隨機分為兩組，對照組給予常規雷貝拉唑鈉腸溶膠囊，20mg/d，早上空腹口服；治療組在對照組的基礎上加服河南中醫學院第一附屬醫院院內製劑——胃痛寧閤劑，30mL/次，3次/d口服，兩組均治療15d。觀察兩組治療前、後主要臨床癥狀及中醫證候積分變化情況。結果：兩組組內治療後與治療前癥狀總積分比較，差異具有統計學意義（P<0.05）；治療後治療組與對照組癥狀總積分比較有顯著性差異（P<0.05），治療組明顯優于對照組；治療組與對照組療效比較有顯著性差異（P<0.05），治療組明顯優于對照組。結論：胃痛寧閤劑聯閤雷貝拉唑鈉腸溶膠囊和單用雷貝拉唑均可改善功能性消化不良上腹痛綜閤徵的臨床癥狀，但胃痛寧閤劑聯閤雷貝拉唑的療效優于常規雷貝拉唑治療。
목적：관찰위통저합제연합뢰패랍서치료공능성소화불량상복통종합정적림상료효。방법：장102례공능성소화불량상복통종합정환자수궤분위량조，대조조급여상규뢰패랍서납장용효낭，20mg/d，조상공복구복；치료조재대조조적기출상가복하남중의학원제일부속의원원내제제——위통저합제，30mL/차，3차/d구복，량조균치료15d。관찰량조치료전、후주요림상증상급중의증후적분변화정황。결과：량조조내치료후여치료전증상총적분비교，차이구유통계학의의（P<0.05）；치료후치료조여대조조증상총적분비교유현저성차이（P<0.05），치료조명현우우대조조；치료조여대조조료효비교유현저성차이（P<0.05），치료조명현우우대조조。결론：위통저합제연합뢰패랍서납장용효낭화단용뢰패랍서균가개선공능성소화불량상복통종합정적림상증상，단위통저합제연합뢰패랍서적료효우우상규뢰패랍서치료。
Objective: To observe clinical effects of the Weitongning decoction plus Bella on functional dyspepsia upper abdominal pain. Methods: 102 cases of functional dyspepsia epigastric pain were randomly divided into two groups. The control group was given conventional rabeprazole sodium enteric coated capsules, 20mg per day, fasting oral in the morning; the treatment group was given the Weitongning decoction more, 30mL per time, orally, 3 times per day, for 15 days. The main clinical symptoms and TCM syndrome scores in the two groups were observed before and after treatment. Results: Before and after treatment in each group, the total symptom score was compared. The difference was statistically significant (P<0.05); after treatment in two groups, the total score of symptoms was compared, with significant difference (P<0.05); the treatment group was significantly better than the control group; the curative effect had significant difference (P<0.05). The treatment group was significantly better than the control group. Conclusion: The Weitongning decoction plus Bella and only Bella can improve the clinical symptoms of functional dyspepsia epigastric pain syndrome, but the curative efficacy of the Weitongning decoction plus Bella is better.
