CAJ | 학술논문

髓炎具有疗效高、复发率低的优点，调节机体免疫应答、降低炎症反应可能是其重要的机制。
수염구유료효고、복발솔저적우점，조절궤체면역응답、강저염증반응가능시기중요적궤제。
Objective: To observe efficacy of the debridement plus TCM medicine on chronic osteomyelitis. Methods: 120 cases of chronic osteomyelitis were randomly divided into the study group and the control group, 60 cases for each group. The control group took conventional surgery and antibiotic treatment; the study group was added the Jiangu decoction. Results: In the study group, the cured, improved, invalid were 37 cases (61.67%), 19 cases (31.67%) and 4 cases (6.67%); In the control group those were 26 cases (43.33%), 21 cases (35.00% ) and 13 cases (21.67%); the difference was statistically significant,Z =-2.392,P=0.017. In the study group WBC, ESR, h-CRP, IL-2, IL-6 and IgG improvement were better,P=0.000. The recurrence rate were 5.4% and 26.9%,x2 = 5.885,P = 0.015. Conclusion: Debridement plus TCM medicine for chronic osteomyelitis can get high efficacy, low recurrence rate, modulation of immune response, and reduce inflammation.