CAJ | 학술논문

目的：分析北京协和医院30年间有不孕症的住院患者的子宫内膜异位症（内异症）的患病情况。方法从北京协和医院住院数据库系统检索1983年5月至2013年11月入院的有不孕症的女性患者，筛选出接受了开腹或腹腔镜妇科手术的病例，总结患者的出院诊断及手术名称，记录内异症、盆腔粘连、子宫肌瘤、输卵管积水、卵巢良性肿瘤（非内异症）、子宫肌腺病的发生情况；收集患者的年龄，分析年龄的变化；比较各年内异症例数的变化。结果共有8857例患者满足本研究的分析要求，其中内异症的发生率为35.50%（95%CI为34.50%～36.49%）；2004年之前内异症发生率不规则波动，2005年开始较稳定地上升；2005年至2013年内异症的发生率比较，差异有统计学意义（P<0.01）。1996年起，接受妇科手术的不孕症患者的平均年龄上升，总体差异显著（P<0.01）；1996年的平均年龄为（29.76±3.74）岁，2013年的平均年龄为（32.85±4.49）岁，两者比较，差异有统计学意义（P<0.01）。诊断为内异症的接受妇科手术的不孕症患者年龄较无内异症者大，分别为（32.67±4.06）、（32.04±4.55）岁，两者比较，差异有统计学意义（P<0.01）；不同年龄组的内异症发生率不同，高年龄组内异症发生率较高（χ2=85.807，P<0.01）。结论不孕症住院患者中内异症的发生率为35.50%，近年内异症的发生率上升。不孕症患者年龄越大，患内异症的风险可能越高。
목적：분석북경협화의원30년간유불잉증적주원환자적자궁내막이위증（내이증）적환병정황。방법종북경협화의원주원수거고계통검색1983년5월지2013년11월입원적유불잉증적녀성환자，사선출접수료개복혹복강경부과수술적병례，총결환자적출원진단급수술명칭，기록내이증、분강점련、자궁기류、수란관적수、란소량성종류（비내이증）、자궁기선병적발생정황；수집환자적년령，분석년령적변화；비교각년내이증례수적변화。결과공유8857례환자만족본연구적분석요구，기중내이증적발생솔위35.50%（95%CI위34.50%～36.49%）；2004년지전내이증발생솔불규칙파동，2005년개시교은정지상승；2005년지2013년내이증적발생솔비교，차이유통계학의의（P<0.01）。1996년기，접수부과수술적불잉증환자적평균년령상승，총체차이현저（P<0.01）；1996년적평균년령위（29.76±3.74）세，2013년적평균년령위（32.85±4.49）세，량자비교，차이유통계학의의（P<0.01）。진단위내이증적접수부과수술적불잉증환자년령교무내이증자대，분별위（32.67±4.06）、（32.04±4.55）세，량자비교，차이유통계학의의（P<0.01）；불동년령조적내이증발생솔불동，고년령조내이증발생솔교고（χ2=85.807，P<0.01）。결론불잉증주원환자중내이증적발생솔위35.50%，근년내이증적발생솔상승。불잉증환자년령월대，환내이증적풍험가능월고。
Objective To analyze the incidence of endometriosis in inpatients with infertility in Peking Union Medical College Hospital in 30 years. Methods The inpatients of Peking Union Medical College Hospital admitted between May 1983 and November 2013 was searched. The infertile patients receiving laparoscopy or laparotomy were included. The discharge diagnosis and the operation were summarized. The incidence of gynecologic diseases were demonstrated, such as endometriosis, pelvic adhesions, uterine fibroid, hydrosalpinx, ovarian benign tumor, and adenomyosis. The age was collected, and the change of age and the incidence of endometriosis was analyzed. Results The incidence of endometriosis in infertile female inpatients was 35.50%(95%CI:34.50%-36.49%). The incidence showed relatively stable increasing tendency after 2004 (with P<0.01). The age had increased significantly since 1996 (with P<0.01);the average age was (29.76±3.74) years old in 1996, and (32.85±4.49) years old in 2013 (P<0.01). The inpatients diagnosed with endometriosis had greater age, (32.67 ± 4.06) versus (32.04 ± 4.55) years old (P<0.01);the incidence of endometriosis differed in different age group, the older group had higher incidence (χ2=85.807, P<0.01). Conclusions Infertile female inpatients showed increasing incidence of endometriosis in recent years. Older infertile patients maybe have higher risk of endometriosis.