CAJ | 학술논문

目的观察滋肾育胎丸对人流术后患者子宫内膜血管内皮生长因子（ VEGF）、雌激素受体（ ER）、孕激素受体（PR）表达的影响，探讨滋肾育胎丸对子宫内膜修复的影响机制。方法69例首次行无痛人流术后患者随机分为两组。对照组自术后两周开始口服维生素E软胶囊，治疗组自术后两周开始口服滋肾育胎丸和维生素E软胶囊。两组均连服14d。两组均经期停药。其后每次月经干净后第1天开始，连服20d，连用2个月经周期。结果治疗组子宫内膜VEGF、PR的表达量均高于对照组（P＜0．05）；两组之间子宫内膜ER的表达量差异无统计学意义（P＞0．05）。结论滋肾育胎丸能促进人流术后子宫内膜VEGF、PR的表达，从而促进生殖功能的恢复。
목적관찰자신육태환대인류술후환자자궁내막혈관내피생장인자（ VEGF）、자격소수체（ ER）、잉격소수체（PR）표체적영향，탐토자신육태환대자궁내막수복적영향궤제。방법69례수차행무통인류술후환자수궤분위량조。대조조자술후량주개시구복유생소E연효낭，치료조자술후량주개시구복자신육태환화유생소E연효낭。량조균련복14d。량조균경기정약。기후매차월경간정후제1천개시，련복20d，련용2개월경주기。결과치료조자궁내막VEGF、PR적표체량균고우대조조（P＜0．05）；량조지간자궁내막ER적표체량차이무통계학의의（P＞0．05）。결론자신육태환능촉진인류술후자궁내막VEGF、PR적표체，종이촉진생식공능적회복。
s:Objective To observe the effect of Zishenyutai pill on the expression of recovery of endometrial vascular endothelial growth factor ( VEGF) , estrogen receptor ( ER) , progesterone receptor ( PR) ,to investigate mechanisms of the Zishenyutai pill on endometrial re-pair.Method 69casesofthefirstlineofthepainlessinducedabortionwererandomlydividedintotwogroups.Thecontrolgroupwerere-quired to take vitamin E capsules for 14 days since the beginning of the two weeks after operation,and the treatment group were required to take Zishenyutai pills and vitamin E capsules for 14 days since the beginning of the two weeks after operation.The two groups were discontin-ued in menstrual period.The next two menstrual cycles take the medicine for 20 consecutive days from the first day of every clean after men-struation.The comparison between the clinical symptoms and the recovery of menstruation were taken in two groups of patients.Re sults There were statistical differences (P<0.05) over the endometrial PR、VEGF values between the two groups, there were no statistical differ-ences ( P>0.05) over the endometrial ER.Conclusion Zishenyutai pills would be promoting pregnancy function recovery after induced a-bortion by advancing the expression of VEGF and PR.