CAJ | 학술논문

目的观察美金刚联合奥卡西平对术后幻肢痛的疗效。方法对骨科20例高位截肢后出现幻肢痛的住院患者口服美金刚联合奥卡西平治疗，观察不同时间疼痛持续时间、程度及药物不良反应。结果10例患者服药1w后临床症状明显缓解，10例患者2w时症状明显减轻。16例患者服药后未有不良反应主诉，2例服药初期有轻度头昏，2例轻度恶心，均未停药，对症处理后缓解。治疗14d末检查血常规、肝功能、肾功能未见异常。结论美金刚联合奥卡西平治疗术后幻肢痛安全有效。
목적관찰미금강연합오잡서평대술후환지통적료효。방법대골과20례고위절지후출현환지통적주원환자구복미금강연합오잡서평치료，관찰불동시간동통지속시간、정도급약물불량반응。결과10례환자복약1w후림상증상명현완해，10례환자2w시증상명현감경。16례환자복약후미유불량반응주소，2례복약초기유경도두혼，2례경도악심，균미정약，대증처리후완해。치료14d말검사혈상규、간공능、신공능미견이상。결론미금강연합오잡서평치료술후환지통안전유효。
Objective To observe the ef ect of Memantine and Oxcarbazepine for phantom limb pain after surgery. Methods 20 inpatient after high level of amputation were treated with various oral doses of Memantine and Oxcarbazepine. Pain-persist during ,pain severity and drug adverse reaction were observed in various time points. Results In half of 20 patients pain relieved completely after 1 week treatment, the other improved obviously in 2 weeks. 16 patients complained of no discomfort, 2 patients had mild dizziness , 2 patients had mild nausea. Al patients remained therapy and had normal routine blood test, liver function and renal function in the end of 14-day-admininstration. Conclusion Memantine and Oxcarbazepine treats phantom limb pain after surgery ef ectly and safely.