医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2015年
22期
94-95
,共2页
布托啡诺%舒芬太尼%自控静脉镇痛
佈託啡諾%舒芬太尼%自控靜脈鎮痛
포탁배낙%서분태니%자공정맥진통
Butorphanol%Sufentanil%Patient-controlled intravenous anagesia
目的：探讨布托啡诺与舒芬太尼等效镇痛剂量用于妇科手术患者自控静脉镇痛（PCIA）的临床效果。方法：60例妇科手术患者随机等分为两组，S组：布托啡诺5mg+舒芬太尼100μg+格拉斯琼9mg；N组：布托啡诺10mg+舒芬太尼50μg+格拉斯琼9mg，两组均加生理盐水配制为150ml。观察并记录苏醒时间及术后2h、12h、24h、36h、48hVAS疼痛评分、不良反应发生例数。结果：两组患者苏醒时间，镇痛效果无明显差异（P＞0.05），N组恶心、呕吐、头晕、皮肤瘙痒发生率低于S组，而嗜睡发生率高于S组（P＜0.05），两组均无呼吸抑制、尿潴留。结论：布托啡诺复合舒芬太尼等效镇痛剂量用于妇科手术患者PCIA镇痛效果均良好，但N组不良反应较少，可作为推荐PCIA方案之一。
目的：探討佈託啡諾與舒芬太尼等效鎮痛劑量用于婦科手術患者自控靜脈鎮痛（PCIA）的臨床效果。方法：60例婦科手術患者隨機等分為兩組，S組：佈託啡諾5mg+舒芬太尼100μg+格拉斯瓊9mg；N組：佈託啡諾10mg+舒芬太尼50μg+格拉斯瓊9mg，兩組均加生理鹽水配製為150ml。觀察併記錄囌醒時間及術後2h、12h、24h、36h、48hVAS疼痛評分、不良反應髮生例數。結果：兩組患者囌醒時間，鎮痛效果無明顯差異（P＞0.05），N組噁心、嘔吐、頭暈、皮膚瘙癢髮生率低于S組，而嗜睡髮生率高于S組（P＜0.05），兩組均無呼吸抑製、尿潴留。結論：佈託啡諾複閤舒芬太尼等效鎮痛劑量用于婦科手術患者PCIA鎮痛效果均良好，但N組不良反應較少，可作為推薦PCIA方案之一。
목적：탐토포탁배낙여서분태니등효진통제량용우부과수술환자자공정맥진통（PCIA）적림상효과。방법：60례부과수술환자수궤등분위량조，S조：포탁배낙5mg+서분태니100μg+격랍사경9mg；N조：포탁배낙10mg+서분태니50μg+격랍사경9mg，량조균가생리염수배제위150ml。관찰병기록소성시간급술후2h、12h、24h、36h、48hVAS동통평분、불량반응발생례수。결과：량조환자소성시간，진통효과무명현차이（P＞0.05），N조악심、구토、두훈、피부소양발생솔저우S조，이기수발생솔고우S조（P＜0.05），량조균무호흡억제、뇨저류。결론：포탁배낙복합서분태니등효진통제량용우부과수술환자PCIA진통효과균량호，단N조불량반응교소，가작위추천PCIA방안지일。
Objective To discuss the clinical effects of combined butorphanol with sufentanil at equivalent dose on patient-controlled intravenous analgesia (PCIA) for gynecologic surgery patients. Methods Sixty gynecologic surgery patients were randomly divided into two groups equally . group S:butorphanol 5 mg+sufentanil 100μg+granisetron 9 mg;group N:butorphanol 10 mg+sufentanil 50μg+granisetron 9 mg. The two formulas were compounded respectively to 150ml analgesic solution with normal saline. The recovery times , VAS pain grades(postoperative 2 h,12 h,24 h,36 h,48 h),cases of adverse reaction on postoperative analgesia were observed and recoded . Results There were no differences on recovery times and analgesia effects(P>0.05).But N group patients had lower incidences of nausea,vomiting, dizziness, cutaneous pruritus and higher incidences of drowsiness than S group patients(P<0.05) and no urinary retention, respiratory depression of two groups patients.Conclusion Butorphanol combine with sufentanil at equivalent dose can both provide satisfactory analgesic effect in PCIA for gynecologic surgery patients and there is fewer adverse reactions in group N and the formula of group N can be one of the recommendations in PCIA.
