CAJ | 학술논문

目的：探讨金葡素、奥沙利铂腹腔内注射联合射频透热治疗恶性腹水的治疗效果。方法：病人分为治疗组和对照组，其中治疗组30例，腹腔内注入金葡素80ml、奥沙利铂200mg/m2+5%葡萄糖水100ml，地塞米松10mg及利卡因10ml；即行射频热疗，一周3次。对照组30例，腹腔内注入金葡素80ml、奥沙利铂200mg/m2+5%葡萄糖水100ml，地塞米松10mg及利卡因10ml。结果：治疗组和对照组治疗腹水的有效率分别为80.0%,53.33%，两组比较差异有显著性（P<0.05）。结论：金葡素、奥沙利铂腹腔内注射联合射频透热治疗恶性腹水有明显的治疗效果。
목적：탐토금포소、오사리박복강내주사연합사빈투열치료악성복수적치료효과。방법：병인분위치료조화대조조，기중치료조30례，복강내주입금포소80ml、오사리박200mg/m2+5%포도당수100ml，지새미송10mg급리잡인10ml；즉행사빈열료，일주3차。대조조30례，복강내주입금포소80ml、오사리박200mg/m2+5%포도당수100ml，지새미송10mg급리잡인10ml。결과：치료조화대조조치료복수적유효솔분별위80.0%,53.33%，량조비교차이유현저성（P<0.05）。결론：금포소、오사리박복강내주사연합사빈투열치료악성복수유명현적치료효과。
Objective: To evaluate the therapeutic effects and adverse reaction of intraperitoneal infusion of staphyiococcus enterotoxin(SE) and oxaliplatin(Oxa) combined with radiofrequency hyperthermia in the treatment of malignant ascites.Methods: A total of 60 cases with malignant ascites were divided into 2 groups. The treatment group (n=30) was treated with SE and oxaliplatin and radiofrequency hyperthermia.The control group(n=30) was treated with SE and oxaliplatin.Results: For the treatment group,CR+PR 80%; the control group, CR+PR 53.33 %.There were significant differences between the two groups (P<0.01).Combined use with SE and Oxa and hyperthermia did not increase the toxicity. Conclusion:The intraperitoneal infusion of staphyiococcus enterotoxin(SE) and oxaliplatin combined with radiofrequency hyperthermia in the treatment of malignant ascites is significantly more effective than that with staphyiococcus enterotoxin(SE) and oxaliplatin.