中国医学装备
中國醫學裝備
중국의학장비
CHINA MEDICAL EQUIPMENT
2015年
9期
95-97,98
,共4页
谢振芳%韩艳%何雅星%刘琴
謝振芳%韓豔%何雅星%劉琴
사진방%한염%하아성%류금
宫颈炎%宫颈环形电极切除术%微波
宮頸炎%宮頸環形電極切除術%微波
궁경염%궁경배형전겁절제술%미파
Cervieitis%Loop electrosurgical excision procedure%Microwave
目的：比较宫颈环形电极切除术(LEEP)与微波治疗慢性宫颈炎的临床疗效。方法：选取134例慢性宫颈炎患者，随机将其分为观察组和对照组，观察组68例，接受LEEP治疗；对照组66例，接受微波治疗；测定治疗前后患者血清肿瘤坏死因子-α(TNF-α)和白细胞介素-6(IL-6)。结果：两组患者轻度慢性宫颈炎的治愈率及总有效率均为100.0%，均无差异；两组患者中度、重度慢性宫颈炎的治愈率及总有效率相比，差异均有统计学意义(x2=14.45，x2=12.43；P＜0.05)。观察组术中出血量、术后阴道排液时间分别为(5.1±3.3)ml、(7.9±3.4)d，均显著低于对照组的(11.5±3.2)ml、(15.1±3.5)d，其差异均有统计学意义(t=11.9，t=12.6；P＜0.05)；观察组术后创面感染发生率、宫颈外翻、宫颈瘢痕率、脱痂出血率以及复发等发生率为0.0%、2.9%、2.9%、2.9%及2.9%，明显低于对照组的6.1%、6.1%、13.6%、15.2%及10.6%，其差异均有统计学意义(x2=11.7，x2=10.8，x2=15.2，x2=15.7，x2=12.3；P＜0.05)。两组治疗后患者血清TNF-α和IL-6均明显降低，观察组治疗后患者血清TNF-α和IL-6明显低于对照组，差异均有统计学意义(P＜0.01)。结论：LEEP用于中度、重度糜烂的慢性宫颈炎，其疗效确切，不良反应小，具有较好的临床应用价值。
目的：比較宮頸環形電極切除術(LEEP)與微波治療慢性宮頸炎的臨床療效。方法：選取134例慢性宮頸炎患者，隨機將其分為觀察組和對照組，觀察組68例，接受LEEP治療；對照組66例，接受微波治療；測定治療前後患者血清腫瘤壞死因子-α(TNF-α)和白細胞介素-6(IL-6)。結果：兩組患者輕度慢性宮頸炎的治愈率及總有效率均為100.0%，均無差異；兩組患者中度、重度慢性宮頸炎的治愈率及總有效率相比，差異均有統計學意義(x2=14.45，x2=12.43；P＜0.05)。觀察組術中齣血量、術後陰道排液時間分彆為(5.1±3.3)ml、(7.9±3.4)d，均顯著低于對照組的(11.5±3.2)ml、(15.1±3.5)d，其差異均有統計學意義(t=11.9，t=12.6；P＜0.05)；觀察組術後創麵感染髮生率、宮頸外翻、宮頸瘢痕率、脫痂齣血率以及複髮等髮生率為0.0%、2.9%、2.9%、2.9%及2.9%，明顯低于對照組的6.1%、6.1%、13.6%、15.2%及10.6%，其差異均有統計學意義(x2=11.7，x2=10.8，x2=15.2，x2=15.7，x2=12.3；P＜0.05)。兩組治療後患者血清TNF-α和IL-6均明顯降低，觀察組治療後患者血清TNF-α和IL-6明顯低于對照組，差異均有統計學意義(P＜0.01)。結論：LEEP用于中度、重度糜爛的慢性宮頸炎，其療效確切，不良反應小，具有較好的臨床應用價值。
목적：비교궁경배형전겁절제술(LEEP)여미파치료만성궁경염적림상료효。방법：선취134례만성궁경염환자，수궤장기분위관찰조화대조조，관찰조68례，접수LEEP치료；대조조66례，접수미파치료；측정치료전후환자혈청종류배사인자-α(TNF-α)화백세포개소-6(IL-6)。결과：량조환자경도만성궁경염적치유솔급총유효솔균위100.0%，균무차이；량조환자중도、중도만성궁경염적치유솔급총유효솔상비，차이균유통계학의의(x2=14.45，x2=12.43；P＜0.05)。관찰조술중출혈량、술후음도배액시간분별위(5.1±3.3)ml、(7.9±3.4)d，균현저저우대조조적(11.5±3.2)ml、(15.1±3.5)d，기차이균유통계학의의(t=11.9，t=12.6；P＜0.05)；관찰조술후창면감염발생솔、궁경외번、궁경반흔솔、탈가출혈솔이급복발등발생솔위0.0%、2.9%、2.9%、2.9%급2.9%，명현저우대조조적6.1%、6.1%、13.6%、15.2%급10.6%，기차이균유통계학의의(x2=11.7，x2=10.8，x2=15.2，x2=15.7，x2=12.3；P＜0.05)。량조치료후환자혈청TNF-α화IL-6균명현강저，관찰조치료후환자혈청TNF-α화IL-6명현저우대조조，차이균유통계학의의(P＜0.01)。결론：LEEP용우중도、중도미란적만성궁경염，기료효학절，불량반응소，구유교호적림상응용개치。
Objective:To compare the effects of Leep knife and microwave on patients with chronic cervicitis. Methods: One hundred and thirty-four patients with chronic cervicitis were randomly divided into two groups, the observation group(n=68 cases) received Leep knife and the control group(n=66 cases) were treated through microwave. Tumor necrosis factor-α(TNF-α)and interleukin-6(IL-6) were detected before and after treatment. Results: The cure rate and total efficicities of the mild chronic cervicitis in the two groups were 100.0%, 94.9% and 100.0%, respectively; that of moderate to severe chronic cervicitis in the two groups were 88.5%, 63.0% and 100.0%, 85.2%(x2=14.45,x2=12.43;P<0.05). The in-traoperative blood loss and the time of vaginal fluid were(5.1±3.3)ml and (7.9±3.4)d, (11.5±3.2)ml and(15.1±3.5)d in the two groups(t=11.9,t=12.6;P<0.05).The incidence of postoperative wound infection, cervical ectropion, cervical scar, exuvial hemorrhage and recurrence were 0.0%, 2.9%, 2.9%, 2.9%, 2.9% in the observation group were lower than those( 6.1%, 6.1%, 13.6%, 15.2%, 10.6%) in the control group(x2=11.7, x2=10.8,x2=15.2,x2=15.7,x2=12.3;P<0.05). The levels of TNF-α and IL-6 decreased after treatment in both groups. There was significant difference between the two groups after treatment(P<0.01). Conclusion: Leep knife could make more significant improvement in the inflammatory status of patients with moderate to severe chronic cervicitis.
