CAJ | 학술논문

目的：探讨血清降钙素原(PCT)、C反应蛋白(CRP)及白细胞(WBC)在急诊留观感染患者中的鉴别诊断价值和联合诊断的意义。方法：选取急诊科留观收治的65例患者，将其分为感染组(44例)和非感染组(21例)，同期选取40例健康体检者为对照组。采用Roche cobas 6000生化免疫一体机检测三组的PCT、CRP及WBC水平。结果：①PCT水平检测结果，感染组明显高于非感染组和健康对照组，差异有统计学意义(F=6.73，P＜0.01)；感染组、非感染组之间CRP、WBC水平无差异，但均明显高于对照组，差异有统计学意义(F=7.77，F=5.49；P＜0.05)；②PCT、CRP和WBC对感染组诊断的灵敏度分别为93.18%，75.01%和43.18%，PCT与CRP联合诊断感染组的灵敏度可达97.73%。结论：PCT指标在判断急诊留观患者感染时优于CRP和WBC指标， PCT与CRP联合检测时可以提高诊断急诊留观患者感染的灵敏度。
목적：탐토혈청강개소원(PCT)、C반응단백(CRP)급백세포(WBC)재급진류관감염환자중적감별진단개치화연합진단적의의。방법：선취급진과류관수치적65례환자，장기분위감염조(44례)화비감염조(21례)，동기선취40례건강체검자위대조조。채용Roche cobas 6000생화면역일체궤검측삼조적PCT、CRP급WBC수평。결과：①PCT수평검측결과，감염조명현고우비감염조화건강대조조，차이유통계학의의(F=6.73，P＜0.01)；감염조、비감염조지간CRP、WBC수평무차이，단균명현고우대조조，차이유통계학의의(F=7.77，F=5.49；P＜0.05)；②PCT、CRP화WBC대감염조진단적령민도분별위93.18%，75.01%화43.18%，PCT여CRP연합진단감염조적령민도가체97.73%。결론：PCT지표재판단급진류관환자감염시우우CRP화WBC지표， PCT여CRP연합검측시가이제고진단급진류관환자감염적령민도。
Objective:To evaluate the clinical significance of the combined determination of procalcitonin(PCT),high-sensitivity C-reactive protein(CRP), white blood cell(WBC) in emergency observation of infection in the differential diagnosis of patients and the diagnosis of joint.Methods: Sixty-five cases (Infection group and non-infection group) with infected in emergency observation selected from October 2014 to March 2015,Then select the healthy persons at the same period as the control group(40 cases),to detect PCT, CRP and WBC levels. Results: (1)PCT infection levels were significantly higher than uninfected and healthy group, and the difference was statistically significant(F=6.73,P<0.01). CRP, WBC levels had no significant difference (F=7.77,F=5.49;P>0.05) between Infection group and non-infection group. (2) PCT, CRP and WBC sensitivity for the diagnosis of infection was 93.18%(41/44), 75.01%(33/44) and 43.18%(19/44), PCT infection and CRP combined sensitivity of up to 97.73% (43/44).Conclusion: In the diagnosis of Emergency observation infection, sensitivity and specificity of PCT were better than CRP and WBC, PCT and CRP test can improve the diagnosis when combined with emergency observation infected with sensitivity.