转化医学电子杂志
轉化醫學電子雜誌
전화의학전자잡지
2015年
6期
67-68
,共2页
甲减%左甲状腺素钠%甲状腺片%临床疗效
甲減%左甲狀腺素鈉%甲狀腺片%臨床療效
갑감%좌갑상선소납%갑상선편%림상료효
hypothyroidism%levothyroxine sodium%thyroid tab-let%clinical efficacy
目的:观察分析左甲状腺素钠联合甲状腺片治疗甲减的临床效果.方法:选取2013?01~12我院收治的25例甲减患者作为对照组,2014?01~12收治的25例甲减患者为观察组.对照组患者给予甲状腺片治疗,观察组患者给予左甲状腺素钠联合甲状腺片治疗,观察比较两组患者的治疗效果、各项指标水平及不良反应情况.结果:观察组治疗总有效率是96%,对照组治疗总有效率是76%,两组比较差异显著,具有统计学意义(P<0.05).观察组血清游离三碘甲腺原氨酸、游离甲状腺素水平显著高于对照组,三酰甘油、总胆固醇、促甲状腺激素水平显著低于对照组,比较差异显著,具有统计学意义(P<0.05).观察组不良反应发生率为4%,对照组不良反应发生率为24%,比较差异显著,具有统计学意义( P <0.05).结论:对甲减患者实施左甲状腺素钠联合甲状腺片治疗能够有效提高治疗效果,改善患者各项指标水平,降低不良反应发生率,值得临床推广应用.
目的:觀察分析左甲狀腺素鈉聯閤甲狀腺片治療甲減的臨床效果.方法:選取2013?01~12我院收治的25例甲減患者作為對照組,2014?01~12收治的25例甲減患者為觀察組.對照組患者給予甲狀腺片治療,觀察組患者給予左甲狀腺素鈉聯閤甲狀腺片治療,觀察比較兩組患者的治療效果、各項指標水平及不良反應情況.結果:觀察組治療總有效率是96%,對照組治療總有效率是76%,兩組比較差異顯著,具有統計學意義(P<0.05).觀察組血清遊離三碘甲腺原氨痠、遊離甲狀腺素水平顯著高于對照組,三酰甘油、總膽固醇、促甲狀腺激素水平顯著低于對照組,比較差異顯著,具有統計學意義(P<0.05).觀察組不良反應髮生率為4%,對照組不良反應髮生率為24%,比較差異顯著,具有統計學意義( P <0.05).結論:對甲減患者實施左甲狀腺素鈉聯閤甲狀腺片治療能夠有效提高治療效果,改善患者各項指標水平,降低不良反應髮生率,值得臨床推廣應用.
목적:관찰분석좌갑상선소납연합갑상선편치료갑감적림상효과.방법:선취2013?01~12아원수치적25례갑감환자작위대조조,2014?01~12수치적25례갑감환자위관찰조.대조조환자급여갑상선편치료,관찰조환자급여좌갑상선소납연합갑상선편치료,관찰비교량조환자적치료효과、각항지표수평급불량반응정황.결과:관찰조치료총유효솔시96%,대조조치료총유효솔시76%,량조비교차이현저,구유통계학의의(P<0.05).관찰조혈청유리삼전갑선원안산、유리갑상선소수평현저고우대조조,삼선감유、총담고순、촉갑상선격소수평현저저우대조조,비교차이현저,구유통계학의의(P<0.05).관찰조불량반응발생솔위4%,대조조불량반응발생솔위24%,비교차이현저,구유통계학의의( P <0.05).결론:대갑감환자실시좌갑상선소납연합갑상선편치료능구유효제고치료효과,개선환자각항지표수평,강저불량반응발생솔,치득림상추엄응용.
AIM: To analyze the clinical effect of levothyroxine sodium combined with thyroid tablets on hypothyroidism. METH?ODS:A total of 25 cases of hypothyroidism patients in our hospi?tal from January to December 2013 were selected as control group, and 25 hypothyroidism patients from January to December 2014 as observation group. The patients in control group received thyroid treatment, while patients in observation group were given levothy?roxine sodium combined thyroid treatment. The treatment effect, all the parameters and adverse reactions of the patients in two groups were compared. RESULTS:The total effective rate of ob?servation group was 96%, and that of control group was 76%. There was a significant difference between two groups ( P <0. 05), with statistical significance. The levels of serum free triio?dothyronine and thyroxine of observation group were significantly higher than the control group, and the levels of triacylglycerol, to?tal cholesterol and thyrotropin of observation group were signifi?cantly lower than the control group with statistical significance (P<0. 05). The observation group showed a lower adverse reac?tion rate compared to control group. The former was 4%, the lat?ter was 24%, and there was a significant difference with statistical significance (P<0. 05). CONCLUSION: The implementation of levothyroxine sodium combined with thyroid tablets on patients with hypothyroidism can effectively improve the treatment effect, level of each index, reduce the incidence of adverse reactions, and is worthy of clinical popularization and application.