CAJ | 학술논문

目的：观察超激光星状神经节照射对头面颈肩部带状疱疹的疗效。方法将头面颈肩部带状疱疹患者53例随机分为对照组与观察组。对照组给予抗病毒、镇痛、营养神经及超激光皮损部位照射治疗。观察组在对照组治疗基础上加用超激光星状神经节照射治疗。评价皮损结痂、疼痛情况，对比两组临床疗效及治疗前后血IL-6、IL-10及IL-2水平。结果两组患者均在治疗3~4d疼痛开始缓解，皮损结痂。观察组疼痛基本消失时间为（5.8±1.03）d，短于对照组，差异有统计学意义（P<0.05）。对照组总有效率为71%，观察组总有效率为84%，观察组总体疗效优于对照组。治疗后1周、1个月、3个月观察组疼痛数字评价量表（numerical rating scale，NRS）评分均低于对照组（P<0.05）。治疗后两组IL-6、IL-10水平降低，IL-2水平升高。治疗后观察组IL-6、IL-10水平低于对照组，IL-2高于对照组（P<0.05）。结论在抗病毒、营养神经、镇痛及局部激光照射基础上加用星状神经节超激光照射治疗可有效缓解疼痛、提高疗效、改善免疫。
목적：관찰초격광성상신경절조사대두면경견부대상포진적료효。방법장두면경견부대상포진환자53례수궤분위대조조여관찰조。대조조급여항병독、진통、영양신경급초격광피손부위조사치료。관찰조재대조조치료기출상가용초격광성상신경절조사치료。평개피손결가、동통정황，대비량조림상료효급치료전후혈IL-6、IL-10급IL-2수평。결과량조환자균재치료3~4d동통개시완해，피손결가。관찰조동통기본소실시간위（5.8±1.03）d，단우대조조，차이유통계학의의（P<0.05）。대조조총유효솔위71%，관찰조총유효솔위84%，관찰조총체료효우우대조조。치료후1주、1개월、3개월관찰조동통수자평개량표（numerical rating scale，NRS）평분균저우대조조（P<0.05）。치료후량조IL-6、IL-10수평강저，IL-2수평승고。치료후관찰조IL-6、IL-10수평저우대조조，IL-2고우대조조（P<0.05）。결론재항병독、영양신경、진통급국부격광조사기출상가용성상신경절초격광조사치료가유효완해동통、제고료효、개선면역。
Objective To observe the effect of super laser irradiating stellate ganglion on head, face, neck and shoulder herpes zoster. Methods Fifty-three patients with head, face, neck and shoulder herpes zoster were randomly divided into control group and observation group. Patients in control group received antiviral, analgesic, neurotrophic and local skin super laser illumination treatment. Patients in observation group were treated with stellate ganglion super laser irradiation based on treatment methods of control group. The incrustation time and pain relief condition were evaluated. Before and after treatment , the serum IL-6, IL-10 and IL-2 levels were measured and compared. Results Three or four days after treatment, the pain began to relieve and skin began to form the scab in two groups. In observation group , the pain totally relief time was shorter than control group. In control group, the total effective rate was 71%. It was higher in observation group reaching to 84%. One week, one month and three months after treatment, the numerical rating scale (NRS) were lower in observation group. After treatment, IL-6, IL-10 reduced and IL-2 elevated in both groups. After treatment, in observation group IL-6, IL-10 were lower and IL-2 was higher than control group (P<0.05). Conclusion On the base of anti-virus, nutrition nerve, analgesia and local laser irradiation, therapy of super laser irradiate stellate ganglion can relieve pain, improve curative effect and immunity.