CAJ | 학술논문

目的：通过点评乳腺癌术后辅助化疗方案中抗肿瘤药物临床应用，验证改进后的 HIS 药学应用基础模块的实用性。方法HIS 药学应用基础模块由具有客户端结构的工作站和工作站应用功能组成。使用信息技术改进后，模块保留原有系统架构，功能扩展：具有临床信息条件筛选、非同源信息共享用户界面和用户操作的功能。用改进模块代替传统人工搜索方法筛选目标病历，对符合纳入条件病历中的抗肿瘤药物医嘱实施人工点评，点评所需信息由改进后的模块提供。进行医嘱点评以检验改进模块的可运行性。结果改进模块筛选出的463份病历，经人工点评后均符合要求。463份病例中使用了 TAC、TC 和 FAC 3个化疗方案，其中使用 TAC 方案的病历中有29份存在不合理用药， TC 方案和 FAC 方案无不合理用药，点评过程中改进模块提供的信息充分，不需启用其它系统收集信息。结论改进的临床药学模块具有较好的可操作性，可以为抗肿瘤药物医嘱点评提供必要的信息支持。
목적：통과점평유선암술후보조화료방안중항종류약물림상응용，험증개진후적 HIS 약학응용기출모괴적실용성。방법HIS 약학응용기출모괴유구유객호단결구적공작참화공작참응용공능조성。사용신식기술개진후，모괴보류원유계통가구，공능확전：구유림상신식조건사선、비동원신식공향용호계면화용호조작적공능。용개진모괴대체전통인공수색방법사선목표병력，대부합납입조건병력중적항종류약물의촉실시인공점평，점평소수신식유개진후적모괴제공。진행의촉점평이검험개진모괴적가운행성。결과개진모괴사선출적463빈병력，경인공점평후균부합요구。463빈병례중사용료 TAC、TC 화 FAC 3개화료방안，기중사용 TAC 방안적병력중유29빈존재불합리용약， TC 방안화 FAC 방안무불합리용약，점평과정중개진모괴제공적신식충분，불수계용기타계통수집신식。결론개진적림상약학모괴구유교호적가조작성，가이위항종류약물의촉점평제공필요적신식지지。
Objective To comment on the clinical application of antitumor drugs in postoperative adjuvant chemotherapy for breast cancer, and to verify the practicability of the modified pharmacy application basic module in Hospital Information System (HIS). Meth-ods HIS pharmacy application basic module was composed of client workstation and application function of workstation. After improved by information technology, the module retained the original system architecture, but extended its functions like conditional screening of clinical information, sharing of user interface and user action. Instead of traditional artificial searching method, we applied the modi-fied module to screen target records, then make artificial review on the medical orders which were confirmed to the conditions. The information needed was provided by the improved module. Results The 463 records selected by the improved module were all meet the requirements after manual review. Three chemotherapy regimens (TAC, TC and FAC) were applied in the 463 cases. Among the medi-cal records of TAC regimen, 29 of them had irrational use of antineoplastic drug. But no irrational drug use was found in TC plan or FAC regimens. During the evaluation process, the module has provided sufficient information, and there was no need to use other system to collect information. Conclusion The improved clinical pharmacy module has good maneuverability, and can provide necessary infor-mation support for evaluation on rationality of antineoplastic drugs.