CAJ | 학술논문

结直肠癌的发生发展受多种因子的调控，对相关调控因素的研究引起学术界的广泛关注。胸苷酸合酶（TS）与结直肠癌的易感性、临床病理特征、化疗效果及预后等均关系密切，本文就结直肠癌组织中 TS 表达及临床意义的研究进展作一综述。
결직장암적발생발전수다충인자적조공，대상관조공인소적연구인기학술계적엄범관주。흉감산합매（TS）여결직장암적역감성、림상병리특정、화료효과급예후등균관계밀절，본문취결직장암조직중 TS 표체급림상의의적연구진전작일종술。
The occurrence and development of colorectal cancer is regulated by a variety of related factors. The study of some regulatory factors has aroused extensive concern in academic circles. Recent studies have shown that thymidylate synthase (TS) is closely related with the susceptivity, clinicopathological features, chemotherapy and prognosis of colorectal cancer. In this review, we mainly discussed the expression and clinical significance of TS in colorectal cancer.