CAJ | 학술논문

目的：探讨舌鳞状细胞癌术后放疗患者口腔溃疡的预防方法。方法收集2012年5月至2014年5月诊治的舌鳞状细胞癌术后放疗患者36例，按照随机数字表法分为对照组和治疗组各18例；对照组给予常规口腔护理，治疗组在常规口腔护理的基础上口服复合维生素B以及应用西吡氯铵漱口液漱口进行加强护理；观察2组患者7d后的口腔溃疡等的发生情况。结果观察期结束时发现治疗组的口腔溃疡发生情况优于对照组（1/18比7/18），字2=-2.372，P<0.05。治疗组口腔洁净度以及口腔护理的总体效果显著优于对照组，Z=-2.093、-2.166，均P<0.05，差异有统计学意义。2组的口腔舒适度比较差异无统计学意义，Z=-1.708，P>0.05。结论舌鳞状细胞癌术后放疗患者进行加强口腔护理能降低口腔溃疡的发生率，有益于口腔健康。
목적：탐토설린상세포암술후방료환자구강궤양적예방방법。방법수집2012년5월지2014년5월진치적설린상세포암술후방료환자36례，안조수궤수자표법분위대조조화치료조각18례；대조조급여상규구강호리，치료조재상규구강호리적기출상구복복합유생소B이급응용서필록안수구액수구진행가강호리；관찰2조환자7d후적구강궤양등적발생정황。결과관찰기결속시발현치료조적구강궤양발생정황우우대조조（1/18비7/18），자2=-2.372，P<0.05。치료조구강길정도이급구강호리적총체효과현저우우대조조，Z=-2.093、-2.166，균P<0.05，차이유통계학의의。2조적구강서괄도비교차이무통계학의의，Z=-1.708，P>0.05。결론설린상세포암술후방료환자진행가강구강호리능강저구강궤양적발생솔，유익우구강건강。
Objective To investigate the preventive effect of oral ulcer using two methods in radio-therapeutic patients after tongue squamous cell carcinoma operation. Methods Thirty-six radiotherapeutic patients after tongue squamous cell carcinoma operation were collected from May 2012 to May 2014 and divided into control group and treatment group according to the random number table method. Regular oral nursing was administered to control group, treatment group were received regular therapy plus orally vitamin B and cetylpyridinium chloride gargle for gargling, and then evaluated the efficacy according related standards. Results Less oral ulcer (1/18 vs.7/18,χ2=-2.372,P<0.05), better oral lustration (Z=-2.093,P<0.05) and overall oral nursing effect (Z=-2.166,P<0.05) were observed in treatment group compared to control group after 7 days of therapy, however, treatment group presented no significantly better comfort level at the same time (Z=-1.708,P>0.05). Conclusions Regular therapy plus orally vitamin B and cetylpyridinium chloride gargle for gargling are effective for the prevention of oral ulcer in radiotherapeutic patients after tongue squamous cell carcinoma operation.