CAJ | 학술논문

目的：观察盐酸羟考酮用于腹腔镜子宫切除术术后镇痛效果。方法60例麻醉风险评分表(ASA)Ⅰ或Ⅱ级择期行腹腔镜子宫切除术患者,随机分为Ⅰ组与Ⅱ组,每组30例。Ⅰ组术后镇痛给予舒芬太尼0.025μg/(kg·h),Ⅱ组给予盐酸羟考酮0.1 mg/(kg·d)。两组术后背景输注速度2 ml/h,总容量100 ml,记录两组术毕(T1)及术后6 h(T2)、12 h(T3)、24 h(T4)与48 h(T5)视觉模拟评分(VAS),记录不良反应发生率。结果两组术后各时点VAS评分均<4分,且两组VAS评分差异无统计学意义(P>0.05),Ⅰ组恶心、呕吐发生率明显高于Ⅱ组,差异有统计学意义(P<0.05)。结论盐酸羟考酮0.1 mg/(kg·d)用于腹腔镜子宫切除术和舒芬太尼0.025μg/(kg·h)具有相同的镇痛效果,同时可降低恶心、呕吐的发生率。
목적：관찰염산간고동용우복강경자궁절제술술후진통효과。방법60례마취풍험평분표(ASA)Ⅰ혹Ⅱ급택기행복강경자궁절제술환자,수궤분위Ⅰ조여Ⅱ조,매조30례。Ⅰ조술후진통급여서분태니0.025μg/(kg·h),Ⅱ조급여염산간고동0.1 mg/(kg·d)。량조술후배경수주속도2 ml/h,총용량100 ml,기록량조술필(T1)급술후6 h(T2)、12 h(T3)、24 h(T4)여48 h(T5)시각모의평분(VAS),기록불량반응발생솔。결과량조술후각시점VAS평분균<4분,차량조VAS평분차이무통계학의의(P>0.05),Ⅰ조악심、구토발생솔명현고우Ⅱ조,차이유통계학의의(P<0.05)。결론염산간고동0.1 mg/(kg·d)용우복강경자궁절제술화서분태니0.025μg/(kg·h)구유상동적진통효과,동시가강저악심、구토적발생솔。
Objective To observe postoperative analgesia effect by oxycodone hydrochlorid in laparoscopic hysterectomy. Methods A total of 60 laparoscopic hysterectomy patients as grade Ⅰ or Ⅱin American society of anesthesiologists scale (ASA) were randomly divided into group Ⅰ and group Ⅱ, and each group contained 30 cases. Group Ⅰ received sufentanil by 0.025 μg/(kg·h) for postoperative analgesia, and group Ⅱ received oxycodone hydrochlorid by 0.1 mg/(kg·d). Both groups had postoperative background infusion speed as 2 ml/h and total volume as 100 ml. Visual analogue scale (VAS) scores were recorded at operation end (T1) and in 6 h (T2), 12 h (T3), 24 h (T4), 48 h (T5) after operation, along with incidence of adverse reactions. Results Both groups had postoperative VAS scores <4 points in each time points. There was no statistically significant difference of VAS scores between the two groups (P>0.05). Group Ⅰ had much higher incidence of nausea and vomiting than group Ⅱ, and their difference had statistical significance (P<0.05). Conclusion Implement of oxycodone hydrochlorid by 0.1 mg/(kg·d) provides similar analgesia effect as sufentanil by 0.025 μg/(kg·h) in laparoscopic hysterectomy, and it can also reduce incidence of nausea and vomiting.