中国循环杂志
中國循環雜誌
중국순배잡지
CHINESE CIRCULATION JOURNAL
2015年
8期
744-748
,共5页
王新洁%梁岩%朱俊%杨艳敏%马文芳%刘明名
王新潔%樑巖%硃俊%楊豔敏%馬文芳%劉明名
왕신길%량암%주준%양염민%마문방%류명명
心房颤动%性别%CHADS2评分%抗凝治疗
心房顫動%性彆%CHADS2評分%抗凝治療
심방전동%성별%CHADS2평분%항응치료
Atrial ifbrillation%Gender%CHADS2score%Anticoagulation
目的:分析不同性别中国急诊就诊的心房颤动患者的临床特征及治疗现状。<br> 方法:2008-11至2011-10在全国20家医院连续入选急诊就诊中有心房颤动诊断的患者,记录患者的基线资料和治疗,按性别将患者分成男女两组,比较两组患者的基线特征及治疗现状。非瓣膜病心房颤动患者卒中风险评估采用CHADS2评分,用Logistic回归分析影响华法林使用的因素。<br> 结果:2015例心房颤动患者中,女性组1104例,男性组911例。与男性患者比较,女性平均年龄较高[(69.11±12.96)岁 vs (67.67±13.63)岁,P=0.015]、体重指数偏低[(23.24±3.73)kg/m2vs (23.89±3.47)kg/m2, P=0.000],合并心力衰竭(39.7% vs 34.6%,P=0.019)、瓣膜病(26.6% vs 12.4%,P=0.000)的比例高,而男性患者吸烟(41.4% vs 5.1%,P=0.000)和合并冠心病(45.1% vs 39.1%,P=0.007)及既往心肌梗死(9.5% vs 5.5%,P=0.001)的比例较女性高。女性非瓣膜病患者CHADS2评分高于男性[(2.0±1.4)分 vs (1.8±1.4)分,P=0.008],且CHADS2评分≥2分比例高于男性(58.0% vs 51%,P=0.005)。407例瓣膜病心房颤动患者中,167例(41%)接受华法林抗凝治疗,其中女性119例(40.5%),男性48例(42.5%)(P=0.713);1608例非瓣膜病心房颤动CHADS2评分≥2分的患者中,接受华法林抗凝治疗的患者仅有105例(12.0%),其中女性54例(11.5%),男性51例(12.5%)(P=0.636)。<br> 结论:中国急诊心房颤动的男、女患者间临床特征及治疗存在差异。女性患者中合并瓣膜病及心力衰竭者较多,男性患者中吸烟及合并冠心病者较多。在抗凝治疗方面,心率快及心力衰竭影响女性使用华法林,合并高血压影响男性使用华法林。
目的:分析不同性彆中國急診就診的心房顫動患者的臨床特徵及治療現狀。<br> 方法:2008-11至2011-10在全國20傢醫院連續入選急診就診中有心房顫動診斷的患者,記錄患者的基線資料和治療,按性彆將患者分成男女兩組,比較兩組患者的基線特徵及治療現狀。非瓣膜病心房顫動患者卒中風險評估採用CHADS2評分,用Logistic迴歸分析影響華法林使用的因素。<br> 結果:2015例心房顫動患者中,女性組1104例,男性組911例。與男性患者比較,女性平均年齡較高[(69.11±12.96)歲 vs (67.67±13.63)歲,P=0.015]、體重指數偏低[(23.24±3.73)kg/m2vs (23.89±3.47)kg/m2, P=0.000],閤併心力衰竭(39.7% vs 34.6%,P=0.019)、瓣膜病(26.6% vs 12.4%,P=0.000)的比例高,而男性患者吸煙(41.4% vs 5.1%,P=0.000)和閤併冠心病(45.1% vs 39.1%,P=0.007)及既往心肌梗死(9.5% vs 5.5%,P=0.001)的比例較女性高。女性非瓣膜病患者CHADS2評分高于男性[(2.0±1.4)分 vs (1.8±1.4)分,P=0.008],且CHADS2評分≥2分比例高于男性(58.0% vs 51%,P=0.005)。407例瓣膜病心房顫動患者中,167例(41%)接受華法林抗凝治療,其中女性119例(40.5%),男性48例(42.5%)(P=0.713);1608例非瓣膜病心房顫動CHADS2評分≥2分的患者中,接受華法林抗凝治療的患者僅有105例(12.0%),其中女性54例(11.5%),男性51例(12.5%)(P=0.636)。<br> 結論:中國急診心房顫動的男、女患者間臨床特徵及治療存在差異。女性患者中閤併瓣膜病及心力衰竭者較多,男性患者中吸煙及閤併冠心病者較多。在抗凝治療方麵,心率快及心力衰竭影響女性使用華法林,閤併高血壓影響男性使用華法林。
목적:분석불동성별중국급진취진적심방전동환자적림상특정급치료현상。<br> 방법:2008-11지2011-10재전국20가의원련속입선급진취진중유심방전동진단적환자,기록환자적기선자료화치료,안성별장환자분성남녀량조,비교량조환자적기선특정급치료현상。비판막병심방전동환자졸중풍험평고채용CHADS2평분,용Logistic회귀분석영향화법림사용적인소。<br> 결과:2015례심방전동환자중,녀성조1104례,남성조911례。여남성환자비교,녀성평균년령교고[(69.11±12.96)세 vs (67.67±13.63)세,P=0.015]、체중지수편저[(23.24±3.73)kg/m2vs (23.89±3.47)kg/m2, P=0.000],합병심력쇠갈(39.7% vs 34.6%,P=0.019)、판막병(26.6% vs 12.4%,P=0.000)적비례고,이남성환자흡연(41.4% vs 5.1%,P=0.000)화합병관심병(45.1% vs 39.1%,P=0.007)급기왕심기경사(9.5% vs 5.5%,P=0.001)적비례교녀성고。녀성비판막병환자CHADS2평분고우남성[(2.0±1.4)분 vs (1.8±1.4)분,P=0.008],차CHADS2평분≥2분비례고우남성(58.0% vs 51%,P=0.005)。407례판막병심방전동환자중,167례(41%)접수화법림항응치료,기중녀성119례(40.5%),남성48례(42.5%)(P=0.713);1608례비판막병심방전동CHADS2평분≥2분적환자중,접수화법림항응치료적환자부유105례(12.0%),기중녀성54례(11.5%),남성51례(12.5%)(P=0.636)。<br> 결론:중국급진심방전동적남、녀환자간림상특정급치료존재차이。녀성환자중합병판막병급심력쇠갈자교다,남성환자중흡연급합병관심병자교다。재항응치료방면,심솔쾌급심력쇠갈영향녀성사용화법림,합병고혈압영향남성사용화법림。
Objective: To analyze the clinical characteristics and current treating status from atrial ifbrillation (AF) patients with different gender in 20 emergency departments. <br> Methods: A total of 2015 consecutive AF patients from 20 emergency departments nationwide from 2008-11 to 2011-10 were retrospectively investigated. The patients were divided into 2 groups: Female group,n=1104 and Male group,n=911. The baseline clinical characteristics and current treating status were compared between groups, the risk of stroke in non-valvular atrial ifbrillation (NVAF) patients was evaluated by CHADS2 score and the factors affecting walfarin application were studied by Logistic regression analysis. <br> Results: Compared with Male group, Female group had the elder age (69.11 ± 12.96) years vs (67.67 ± 13.63) years,P=0.015, lower body mass index (BMI) (23.24 ± 3.73) kg/m2 vs (23.89 ± 3.47) kg/m2,P=0.000, more patients combining with heart failure (39.7% vs 34.6%,P=0.019), more patients with valvular heart disease (26.6% vs 12.4%,P=0.000). In contrast, Male group had more smokers (41.4% vs 5.1%,P=0.000), more patients combining with coronary artery disease (45.1% vs 39.1%,P=0.007) and more patients with previous history of myocardial infarction (9.5% vs 5.5%,P=0.001). The average CHADS2 score was higher in Female group than Male group (2.0 ± 1.4) vs (1.8 ± 1.4),P=0.008 and the proportion of patients with CHADS2 score ≥2 was higher in Female group than Male group (58.0% vs 51%,P=0.005). There were 407 patients of valvular heart disease with AF and 167 (41%) of them received walfarin treatment including 119 female and 48 male,P=0.713; 1608 NVAF patients with CHADS2 score≥ 2 and 105 of them received anticoagulation therapy including 54 female and 51 male,P=0.636. <br> Conclusion: The clinical characteristics and current treating status are different by gender from AF patients in 20 emergency departments in China.