CAJ | 학술논문

目的：探讨亚临床甲状腺功能减退与自然流产的相关性,以避免反复流产的发生,提高正常妊娠率。方法150例早孕妇女作为研究对象,有2次及2次以上自然流产史为 A 组,1次自然流产史为 B 组,无不良孕史为 C 组,各50例。用电化学发光法检测并比较促甲状腺素(TSH)和游离甲状腺素(FT4)。结果亚临床甲状腺功能减退患病率 A 组28.00%, B 组22.00%, C 组6.00%。A 组与 B 组比较,差异无统计学意义(P>0.05)；A 组与 C 组、B 组与 C 组比较,差异均有统计学意义(P<0.05)。结论亚临床甲状腺功能减退与自然流产有明显相关性,与自然流产次数无明显相关性,对于有不良孕史早孕妇女应常规筛查并尽早积极治疗。
목적：탐토아림상갑상선공능감퇴여자연유산적상관성,이피면반복유산적발생,제고정상임신솔。방법150례조잉부녀작위연구대상,유2차급2차이상자연유산사위 A 조,1차자연유산사위 B 조,무불량잉사위 C 조,각50례。용전화학발광법검측병비교촉갑상선소(TSH)화유리갑상선소(FT4)。결과아림상갑상선공능감퇴환병솔 A 조28.00%, B 조22.00%, C 조6.00%。A 조여 B 조비교,차이무통계학의의(P>0.05)；A 조여 C 조、B 조여 C 조비교,차이균유통계학의의(P<0.05)。결론아림상갑상선공능감퇴여자연유산유명현상관성,여자연유산차수무명현상관성,대우유불량잉사조잉부녀응상규사사병진조적겁치료。
Objective To investigate correlation between subclinical hypothyroidism and spontaneous abortion, in order to avoid recurrent abortion and to improve rate of normal pregnancy. Methods There were 150 early pregnancy women as study subjects. Group A contained patients with twice or more spontaneous abortion, group B contained patients with once spontaneous abortion, group C contained patients without bad pregnancy history, and each group contained 50 cases. Electrochemiluminescence was applied to compare thyroid stimulating hormone (TSH) and free thyroxine (FT4). Results Subclinical hypothyroidism accounted for 28.00% in group A, 22.00% in group B and 6.00% in group C. There was no statistically significant difference between group A and group B (P>0.05). The differences between group A and group B, group A and group C all had statistical significance (P<0.05). Conclusion There is an obvious correlation between subclinical hypothyroidism and spontaneous abortion, while subclinical hypothyroidism is not correlated with time of spontaneous abortion. Conventional screening and timely treatment are necessary for early pregnancy women with bad pregnancy history.