CAJ | 학술논문

目的：探讨脓毒症休克患者凝血功能及血浆蛋白C水平与预后的相关性研究。方法：收集我院近3年共83例诊断为脓毒症的患者作为研究对象，按患者预后分为病例组(脓毒症休克存活患者)和对照组(脓毒症休克死亡患者)。比较对照组和病例组凝血指标及血浆蛋白C。结果：对照组凝血酶原时间、凝血酶时间、活化部分凝血酶时间、D-二聚体、纤维蛋白原及血浆蛋白C明显高于病例组(P<0.05)。结论：本次研究认为凝血指标中凝血酶原时间、D-二聚体与脓毒症休克病情严重程度及预后有一定相关，及早干预并治疗凝血功能紊乱，对于提高患者的存活率有积极的意义。
목적：탐토농독증휴극환자응혈공능급혈장단백C수평여예후적상관성연구。방법：수집아원근3년공83례진단위농독증적환자작위연구대상，안환자예후분위병례조(농독증휴극존활환자)화대조조(농독증휴극사망환자)。비교대조조화병례조응혈지표급혈장단백C。결과：대조조응혈매원시간、응혈매시간、활화부분응혈매시간、D-이취체、섬유단백원급혈장단백C명현고우병례조(P<0.05)。결론：본차연구인위응혈지표중응혈매원시간、D-이취체여농독증휴극병정엄중정도급예후유일정상관，급조간예병치료응혈공능문란，대우제고환자적존활솔유적겁적의의。
Objective To investigate the correlation of blood coagulation function and plasma protein level with prognosis. Methods: 83 patients with sepsis were divided into survival group and death group,and the coagulation index and plasma protein C of the two groups were compared. Results The prothrombin time,thrombin time, activated partial thromboplastin time, D- dimer, fibrinogen and plasma protein C were significantly higher death in group in than survival group (P<0.05). Conclusion This study suggests that there is a certain correlation of prothrombin time and D- dimer with the severity and prognosis of septic sheck, early intervention and treatment of coagulation disorders may improve the survival rate of patients.