CAJ | 학술논문

目的：探讨18F-FDG PET/CT全身显像评估非小细胞肺癌纵隔淋巴结转移的诊断价值。方法：回顾性的分析了2013年5月至2015年1月在我院呼吸科和胸外科疑似肺癌的患者在我科行18F-FDG PET/CT检查后，能够手术的患者均在检查后1周内在我院胸外科行原发灶及相应肺叶切除+系统淋巴结清扫，其中有82例患者经病理和免疫组化证实为非小细胞肺癌，以术后病理检查结果作为“金标准”，分析18F-FDG PET/CT在非小细胞肺癌纵隔淋巴结转移的灵敏度、特异性、准确性、阳性预测值和阴性预测值。结果：82例非小细胞肺癌病理证实36例有淋巴结转移，18F-FDG PET/CT显像诊断非小细胞肺癌淋巴结转移的灵敏度、特异性、准确性、阳性预测值和阴性预测值分别为72.22豫、84.78豫、79.27豫、78.79豫、79.59豫。结论：18F-FDG PET/CT能较准确评估非小细胞肺癌纵隔淋巴结转移。
목적：탐토18F-FDG PET/CT전신현상평고비소세포폐암종격림파결전이적진단개치。방법：회고성적분석료2013년5월지2015년1월재아원호흡과화흉외과의사폐암적환자재아과행18F-FDG PET/CT검사후，능구수술적환자균재검사후1주내재아원흉외과행원발조급상응폐협절제+계통림파결청소，기중유82례환자경병리화면역조화증실위비소세포폐암，이술후병리검사결과작위“금표준”，분석18F-FDG PET/CT재비소세포폐암종격림파결전이적령민도、특이성、준학성、양성예측치화음성예측치。결과：82례비소세포폐암병리증실36례유림파결전이，18F-FDG PET/CT현상진단비소세포폐암림파결전이적령민도、특이성、준학성、양성예측치화음성예측치분별위72.22예、84.78예、79.27예、78.79예、79.59예。결론：18F-FDG PET/CT능교준학평고비소세포폐암종격림파결전이。
ObjectiveTo investigate the value of positron emission tomographic-computed tomographic (PET/CT) scan in the diagnosis of mediastinal lymph node metastasis in patients with non-small cell lung cancer (NSCLC). Methods: The 18F-FDG PET/CT examinations of patients who were suspicious of lung cancer from department of respiratory and thoracic surgery in our hospital were performed during May 2013 to Jan 2015. All patients underwent radical surgery and mediastinal lymph node dissection within one week after the 18F-FDG PET/CT scan. Eighty-two patients were finally confirmed to have NSCLC with the histopathological and immunocytochemcal results as the reference standard. The diagnostic sensitivity, specificity, accuracy of positive and negative predictive values of 18F-FDG PET/CT were all analyzed. Results Mediastinal lymph nodes were histologically confirmed in 36 of 82 patients. The sensitivity, specificity, accuracy, accuracy of positive and negative predictive values of 18F-FDG PET/CT for identifying mediastinal lymph nodes involvement were 72.22%, 84.78%,79.27%,78.79%and 79.59%, respectively. Conclusion 18F-FDG PET/CT may be useful to assess mediastinal lymph node metastasis in NSCLC patients.