CAJ | 학술논문

目的：：研究18F-脱氧葡萄糖(FDG)PET/CT显像对甲状腺显影病变性质分析及最大标准摄取值(SUVmax)与甲状腺良恶性病变的相关性。方法：收集从2011年6月至2013年12月中来我科行18F-FDG PET/CT全身显像中甲状腺弥漫性及局灶性摄取病人共113例，所有病例最终诊断依靠甲状腺细针穿刺、手术病理、甲功五项及6个月随访观察证实，并进行良恶性病灶相关性分析。结果：甲状腺单侧或双侧弥漫性显影病人34例，其中甲状腺功能亢进2例，原发性甲状腺淋巴瘤3例，淋巴瘤累及甲状腺1例，1例为亚急性甲状腺炎，桥本氏甲状腺炎27例，良恶性比例为7.5：1；甲状腺局灶性显影79例，其中良性病变46例，恶性病变33例，恶性比例为41.7%。良恶性结节SUVmax有明显统计学意义，分别为(4.47±1.37与7.07±1.22，t=8.702, P<0.05)。结论：18F-FDG PET/CT显像中甲状腺弥漫性显影以良性病变为主，且多为甲状腺炎症,；局灶性甲状腺显影中，虽甲状腺恶性病变比例较高，但单存的SUV值无法鉴别其良恶性。在良恶性结节SUVmax值比较中，SUVmax值越高，其恶性可能性越大。
목적：：연구18F-탈양포도당(FDG)PET/CT현상대갑상선현영병변성질분석급최대표준섭취치(SUVmax)여갑상선량악성병변적상관성。방법：수집종2011년6월지2013년12월중래아과행18F-FDG PET/CT전신현상중갑상선미만성급국조성섭취병인공113례，소유병례최종진단의고갑상선세침천자、수술병리、갑공오항급6개월수방관찰증실，병진행량악성병조상관성분석。결과：갑상선단측혹쌍측미만성현영병인34례，기중갑상선공능항진2례，원발성갑상선림파류3례，림파류루급갑상선1례，1례위아급성갑상선염，교본씨갑상선염27례，량악성비례위7.5：1；갑상선국조성현영79례，기중량성병변46례，악성병변33례，악성비례위41.7%。량악성결절SUVmax유명현통계학의의，분별위(4.47±1.37여7.07±1.22，t=8.702, P<0.05)。결론：18F-FDG PET/CT현상중갑상선미만성현영이량성병변위주，차다위갑상선염증,；국조성갑상선현영중，수갑상선악성병변비례교고，단단존적SUV치무법감별기량악성。재량악성결절SUVmax치비교중，SUVmax치월고，기악성가능성월대。
Objective To evaluate the value of increased thyroid gland uptake and the clinical significance of SUVmax in distinguishing thyroid benign diseases from malignant diseases via 18F-FDG PET/CT. Methods:113 cases with focal or diffuse FDG uptake in thyroid were collected and retrospectively analyzed. Final diagnosis of all cases based on fine-needle aspiration,surgical operation, measurement of thyroid hormone, and 6 months follow-up studies. The data were correlatively analysed. Results There were 34 patients with unilateral or bilateral diffuse thyroid imaging,including 2 cases of hyperthyroidism, 3 cases of primary thyroid lymphoma,1 case of secondary thyroid lymphoma, 1 case of subacute thyroiditis,and 27 cases of Hashimoto disease. The ratio of benign to malignant was 7.5:1. Of the 79 patients with focal thyroid imaging,46 cases were benign and 33 were maglinant, maglinant lesions accounted for 41.7%. The SUVmax of benign and malignant thyroid nodules were 4.47±1.37 and 7.07±1.22,respectively,having statistical difference(P<0.05). ConclusionThe diffuse thy-roid uptake mostly indicates benign thyroid disease, most of which are thyroid inflammation. Although lesion with focal uptake is more likely to be malignant. However, SUVmax alone cannot discrimate the malignancy. In comparison of the value of benign and maglinant lesion, the higher the value of SUVmax,the greater possibility of malignance is.