CAJ | 학술논문

目的：探讨该院手足口病标本病毒检测结果观察。方法回顾性分析2014年4—7月在该院治疗的300例手足口病患者的临床资料，分别采用咽拭子标本和粪便标本进行病原学检测，分析检测结果。结果所有患者中，肠道病毒(EV)检出率为90.67%，其中肠道病毒71型(EV71)占62.13%，柯萨奇病毒A16(CA16)占16.18%，其他EV亚型占21.69%；粪便标本EV71检出率高于咽拭子标本，差异有统计学意义(P<0.05)；男女比例无明显差异，发病主要集中在1~3岁，达76%，尤以1岁内发病率最高，达48.67%。结论手足口病由感染EV引起，以EV71和CA16最为高发，粪便标本的检出率更高，加强EV71和CA16的检测有助于提高手足口病的防范和控制。
목적：탐토해원수족구병표본병독검측결과관찰。방법회고성분석2014년4—7월재해원치료적300례수족구병환자적림상자료，분별채용인식자표본화분편표본진행병원학검측，분석검측결과。결과소유환자중，장도병독(EV)검출솔위90.67%，기중장도병독71형(EV71)점62.13%，가살기병독A16(CA16)점16.18%，기타EV아형점21.69%；분편표본EV71검출솔고우인식자표본，차이유통계학의의(P<0.05)；남녀비례무명현차이，발병주요집중재1~3세，체76%，우이1세내발병솔최고，체48.67%。결론수족구병유감염EV인기，이EV71화CA16최위고발，분편표본적검출솔경고，가강EV71화CA16적검측유조우제고수족구병적방범화공제。
Objective To investigate the virus detection results of specimens of hand, foot and Mouth. Methods The clinical data of 300 cases with hand, foot and mouth disease which were treated in our hospital during April 2014 to July 2014 were retrospec-tively analyzed, the throat swab specimens and the stool specimens were respectively used to detect the pathogen, and the results were analyzed. Results All patients, the enterovirus (EV) detection rate was 90.67%, the type of enterovirus 71 (EV71) accounted for 62.13%, coxsackie virus A16 (CA16) accounted for 16.18%, other EV subtype accounted for 21.69%; Stool specimens EV71 detection rate was higher than pharyngeal swab specimens, the difference was statistically significant (P< 0.05); Ratio of male to female was not significant difference, mainly concentrated in 1 to 3 years old, the incidence was up to76%, especially within 1 year of age, up to 48.67%. Conclusion Hand, foot and mouth disease caused by infection with EV, EV71 and CA16 were the highest, and the feces specimen detection rate was higher, the detection of EV71 and CA16 was helpful to improve the prevention and control of hand foot mouth disease.