CAJ | 학술논문

目的：通过对286例呼吸道合胞病毒（RSV）毛细支气管炎患儿临床分析，探讨病毒多重感染对其严重度的影响。方法对286例RSV毛细支气管炎进行多种病毒抗体检测，观察病毒多重感染对不同程度的RSV毛细支气管炎的影响。结果 RSV毛细支气管炎合并感染的比例达29．37％，以双重感染为主；与单纯RSV感染相比，合并感染患儿重症病例明显增多（χ2＝128．7，P＜0．01）。结论 RSV毛细支气管炎合并其他呼吸道病毒感染并不少见，病毒多重感染可以加重疾病的严重程度。
목적：통과대286례호흡도합포병독（RSV）모세지기관염환인림상분석，탐토병독다중감염대기엄중도적영향。방법대286례RSV모세지기관염진행다충병독항체검측，관찰병독다중감염대불동정도적RSV모세지기관염적영향。결과 RSV모세지기관염합병감염적비례체29．37％，이쌍중감염위주；여단순RSV감염상비，합병감염환인중증병례명현증다（χ2＝128．7，P＜0．01）。결론 RSV모세지기관염합병기타호흡도병독감염병불소견，병독다중감염가이가중질병적엄중정도。
Objective To investigate the effects of virus coinfection on the severity of respiratory syncytial virus(RSV)bronchiolitis through the clinical analysis of 286 cases.Methods Various virus antibody were measured by using ELISA in 286 cases of RSV bronchiolitis.The frequency of respiratory virus coinfection on the severity of RSV bronchiolitis was observed.Results RSV bronchiolitis complicated with virus coinfection ratio reached 29.37%,especially with the double infection.Compared to patients with RSV infection,the severe cases increased sig-nificantly in patients with virus coinfection(χ2 =128.7,P<0.01).Conclusion Other respiratory viruses coinfection are not uncommon in infants with RSV bronchiolitis and may increase the severity of RSV bronchiolitis.